CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Revenue:
Revenue	$ 194,032	$ 141,236	$ 104,541
Costs and operating expenses:
Cost of product revenue	86,531	67,050	47,117
Research and development	15,821	8,672	7,355
Selling, general and administrative	65,692	51,509	30,853
Contingent consideration – fair value adjustments	0		3,242
Total costs and operating expenses	168,044	127,231	88,567
Income from operations	25,988	14,005	15,974
Other income (expenses):
Investment income	1,895	371	346
Interest expense	(6,709)	(6,441)	(3,768)
Other income (expenses)	262	(687)	(860)
Other expenses, net	(4,552)	(6,757)	(4,282)
Income before income taxes	21,436	7,248	11,692
Income tax provision (benefit)	4,819	(21,105)	11
Net income	$ 16,617	$ 28,353	$ 11,681
Earnings per share:
Basic	$ 0.38	$ 0.74	$ 0.35
Diluted	$ 0.37	$ 0.72	$ 0.34
Weighted average common shares outstanding:
Basic	43,767	38,234	33,573
Diluted	45,471	39,150	34,099
Net income	$ 16,617	$ 28,353	$ 11,681
Other comprehensive income (loss):
Foreign currency translation adjustment	(5,530)	7,381	(5,189)
Unrealized gain on marketable securities	0	5	6
Comprehensive income	11,087	35,739	6,498
Products
Revenue:
Revenue	193,891	141,089	104,441
Royalty and Other Revenue
Revenue:
Revenue	$ 141	$ 147	$ 100