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Fair Value Measurement - Additional Information (Detail) € in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2015 USD ($)	Sep. 30, 2014 USD ($)	Sep. 30, 2015 USD ($)	Sep. 30, 2015 EUR (€)	Sep. 30, 2014 USD ($)	Dec. 31, 2016 USD ($)	Dec. 31, 2015 USD ($)	Jun. 02, 2014 USD ($)
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Fair value of other assets	$ 0		$ 0
Fair value of other liabilities	0		0
Increase to milestone payment	233,000	$ 10,000	2,114,000		$ 126,000
Payment of contingent considerations			99,000		$ 604,000
Accrued Balance								$ 1,370,000
Refine Technology, LLC
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Increase to milestone payment			2,088,000
Refine Technology, LLC \| Milestone Payments
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Payment of contingent considerations			1,000,000
Accrued Balance								$ 1,370,000
Bio Flash \| Minimum
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Royalty payment			110,000
Novozymes Biopharma DK A/S Sweden Ab \| Milestone Payments
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Payment of contingent considerations			29,000	€ 25
Significant unobservable inputs (Level 3) \| Refine Technology, LLC \| Milestone Payments
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Increase to milestone payment			2,088,000
Accrued Balance	$ 4,409,000		$ 4,409,000
Scenario, Forecast \| Significant unobservable inputs (Level 3) \| Refine Technology, LLC \| Milestone Payments
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Accrued Balance						$ 85,000	$ 4,409,000