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Revenue Recognition - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Sep. 03, 2014
Jan. 30, 2014
Sep. 30, 2014
Jun. 30, 2015
Mar. 31, 2014
Jun. 30, 2015
Jun. 30, 2014
Dec. 31, 2014
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]                
Revenue recognized           $ 2,115,000    
Non-refundable up-front payment           2,000,000    
Payment to be received upon signing of agreement           125,675    
Revenue recognized under revenue recognition, up front payment         $ 2,000,000      
Royalty and other revenue             $ 1,991,166  
Technology Transfer                
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]                
Revenue recognized             $ 0  
Estimated selling price       $ 300,000   300,000    
Consideration allocated to transaction       11,000   11,000    
Royalty and other revenue     $ 125,675          
Clinical Development                
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]                
Milestone Payment           60,000,000    
Potential milestone payments to be received       60,000,000   60,000,000    
Initial Commercial Sales                
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]                
Potential milestone payments to be received       100,000,000   100,000,000    
BioMarin Pharmaceutical, Inc. | Asset Purchase Agreement                
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]                
Upfront payment received under purchase agreement   $ 2,000,000            
Potential milestone payments to be received       160,000,000   160,000,000    
Provision for refund           0    
Revenue recognized       $ 0   $ 0   $ 2,100,000
BioMarin Pharmaceutical, Inc. | Clinical Development | Asset Purchase Agreement                
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]                
Percentage relate to clinical development from Milestone payment           37.00%    
BioMarin Pharmaceutical, Inc. | Initial Commercial Sales | Asset Purchase Agreement                
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]                
Percentage relate to clinical development from Milestone payment           63.00%    
BioMarin Pharmaceutical, Inc. | Technology Transfer Payments | Asset Purchase Agreement                
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]                
Milestone Payment $ 125,675