Income Taxes - Additional Information (Detail) (USD $)	12 Months Ended
	Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012
Income Taxes [Line Items]
Deferred tax assets from share-based payments	$ 6,377,000
Valuation allowance increase (decrease)	727,000	(1,736,000)	(10,169,000)
Cumulative pre-tax income position, Year			3 years
Reversed of deferred tax asset valuation allowance			3,021,000
Provision for open audit matters,impact of interest, penalties and other factors		800,000
Impact of unrecognized tax benefits on effective tax rate	2,080,566
Interest and penalties related to uncertain tax positions	139,000
Accrued interest and penalties related to uncertain tax positions	274,000
Earnings of foreign subsidiaries permanently reinvest outside the U.S	16,498,000
ImClone
Income Taxes [Line Items]
Litigation settlements	40,000,000
Orencia Royalties from Bristol
Income Taxes [Line Items]
Litigation settlements	5,000,000
Tax assessments period one
Income Taxes [Line Items]
Tax years undergoing audit	March 31, 2008 through 2011
Tax assessments period one | Including potential penalties
Income Taxes [Line Items]
Future tax assessments loss	856,000
Tax assessments period one | Research and Development Credit
Income Taxes [Line Items]
Future tax assessments loss	713,000
Tax assessments period two | Research and Development Credit
Income Taxes [Line Items]
Provision for open audit matters,impact of interest, penalties and other factors	125,000
Maximum
Income Taxes [Line Items]
Net operating loss and business tax credit carry forwards expiration date	At various dates through December 2032
Future tax assessments loss	1,383,000
Maximum | Including potential penalties
Income Taxes [Line Items]
Future tax assessments loss	1,659,000
Available to Reduce Future Federal Income Taxes
Income Taxes [Line Items]
Net operating loss carry forwards	43,387,000
Business tax credit carry forwards	1,782,000		2,160,000
Reserves for business tax credits		$ 1,117,000