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Percentage of Revenue from Significant Customers (Detail) (Sales)
3 Months Ended 6 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Jun. 30, 2012
Orencia Royalties from Bristol
       
Revenue, Major Customer [Line Items]        
Concentration risk percentage 25.00% 23.00% 24.00% 23.00%
Bioprocessing Customer A
       
Revenue, Major Customer [Line Items]        
Concentration risk percentage 39.00% 44.00% 38.00% 44.00%
Bioprocessing Customer B
       
Revenue, Major Customer [Line Items]        
Concentration risk percentage 15.00% 11.00% 14.00% 13.00%
Bioprocessing Customer C
       
Revenue, Major Customer [Line Items]        
Concentration risk percentage 10.00% 14.00% 13.00% 12.00%