Commitments and Contingencies - Additional Information (Detail) (USD $)	3 Months Ended								9 Months Ended		12 Months Ended						9 Months Ended		12 Months Ended					9 Months Ended	12 Months Ended
	Dec. 31, 2012	Sep. 30, 2012	Jun. 30, 2012	Mar. 31, 2012	Dec. 31, 2011	Sep. 30, 2011	Jun. 30, 2011	Mar. 31, 2011	Dec. 31, 2011	Dec. 31, 2010	Dec. 31, 2012 Building sqft	Jul. 31, 2011 sqft	Mar. 31, 2011	Mar. 31, 2008 sqft	Mar. 31, 2007 sqft	Mar. 31, 2001 sqft	Dec. 31, 2011 Licensing Agreements	Dec. 31, 2010 Licensing Agreements	Dec. 31, 2012 Licensing Agreements	Mar. 31, 2011 Licensing Agreements	Mar. 31, 2010 Licensing Agreements License Fees	Mar. 31, 2011 Licensing Agreements Sub License Fees	Mar. 31, 2010 Licensing Agreements Sub License Fees	Dec. 31, 2011 Licensing Agreements Milestone Payable	Dec. 31, 2012 Lease for three buildings sqft	Dec. 31, 2012 Lease for the fourth building sqft
Commitments and Contingencies [Line Items]
Lease agreement, term												11 years		2 years	5 years	10 years
Lease agreement, space											45,000	56,000		7,350	2,500	25,000									41,000	4,000
Lease agreement, expiration date												May 31, 2023													Jun. 30, 2017	Sep. 30, 2019
Lease agreement, letter of credit issued												$ 200,000
Lease agreement, number buildings leased											4
Operating leases, rent expense									528,000	510,000	2,183,000		686,000
Operating leases, deferred rent liabilities	329,000				15,000				15,000		329,000
Research and development expenses	2,343,000	2,433,000	2,906,000	2,808,000	2,870,000	3,075,000	3,517,000	3,785,000	9,461,960	8,744,548	10,489,811		12,528,819				525,000	343,000	55,000	374,000	500,000	65,000	175,000	500,000
Research and development, financial obligation																			16,000,000
Purchase Orders, Supply Agreements and Other Contractual Obligations	$ 2,872,000										$ 2,872,000