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Cover Page - USD ($)
 12 Months Ended
Dec. 31, 2022
Feb. 17, 2023
Jun. 30, 2022
Cover [Abstract]      
Amendment Flag false    
Document Type 10-K    
Document Fiscal Year Focus 2022    
Document Fiscal Period Focus FY    
Entity Central Index Key 0000730272    
Current Fiscal Year End Date --12-31    
Document Period End Date Dec. 31, 2022    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Securities Act File Number 000-14656    
Entity Registrant Name REPLIGEN CORP    
Entity Filer Category Large Accelerated Filer    
Trading Symbol RGEN    
Title of 12(b) Security Common Stock    
Security Exchange Name NASDAQ    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 04-2729386    
Entity Address, Address Line One 41 Seyon Street, Bldg. 1, Suite 100    
Entity Address, City or Town Waltham    
Entity Address, State or Province MA    
Entity Address, Postal Zip Code 02453    
City Area Code 781    
Entity Shell Company false    
Smaller reporting company false    
Emerging growth company false    
Local Phone Number 250-0111    
Document Annual Report true    
Document Transition Report false    
Entity Voluntary Filers No    
Entity Well-known Seasoned Issuer Yes    
Entity Public Float     $ 8,911,722,244
Entity Common Stock, Shares Outstanding   55,562,583  
ICFR Auditor Attestation Flag true    
Documents Incorporated by Reference

Documents Incorporated By Reference

The registrant intends to file a proxy statement pursuant to Regulation 14A within 120 days of the end of the fiscal year ended December 31, 2022. Portions of such proxy statement are incorporated by reference into Part III of this Annual Report on Form 10-K.

   
Auditor Firm Id 42    
Auditor Firm Name Ernst & Young LLP    
Auditor Firm Location Boston, Massachusetts, United States