CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Revenue:
Revenue	$ 200,741	$ 178,216	$ 614,774	$ 484,013
Costs and operating expenses:
Cost of product revenue	86,514	75,495	255,130	197,232
Research and development	10,228	9,154	32,823	25,155
Selling, general and administrative	53,643	48,373	162,592	131,809
Contingent consideration	(2,309)	0	(11,604)	0
Total costs and operating expenses	148,076	133,022	438,941	354,196
Income from operations	52,665	45,194	175,833	129,817
Other income (expenses):
Investment income	2,177	44	2,962	137
Interest expense	(329)	(2,859)	(892)	(8,400)
Amortization of debt issuance costs	(455)	(361)	(1,360)	(1,070)
Other expenses	(6,591)	(786)	(10,389)	(1,789)
Other expenses, net	(5,198)	(3,962)	(9,679)	(11,122)
Income before income taxes	47,467	41,232	166,154	118,695
Income tax provision	7,062	7,734	28,924	19,514
Net income	$ 40,405	$ 33,498	$ 137,230	$ 99,181
Earnings per share:
Basic	$ 0.73	$ 0.61	$ 2.48	$ 1.81
Diluted (Note 12)	$ 0.71	$ 0.58	$ 2.39	$ 1.74
Weighted average common shares outstanding:
Basic	55,498	55,015	55,432	54,918
Diluted (Note 12)	57,304	57,368	57,598	57,072
Net income	$ 40,405	$ 33,498	$ 137,230	$ 99,181
Other comprehensive income (loss):
Foreign currency translation adjustment	(18,170)	(5,550)	(38,375)	(12,004)
Comprehensive income	22,235	27,948	98,855	87,177
Products
Revenue:
Revenue	200,708	178,177	614,668	483,834
Royalty and other revenue
Revenue:
Revenue	$ 33	$ 39	$ 106	$ 179