<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS FINANIAL INFORMATION EXTRACTED FROM THE FINANCIAL
STATEMENTS FOR REPLIGEN CORPORATION AND IS QUALIFIED IN ITS ENTIRETY BY
REFERENCE TO SUCH FINANCIAL STATEMENTS.


                             
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          MAR-31-2000
<PERIOD-END>                               MAR-31-2000
<CASH>                                          25,227
<SECURITIES>                                     8,806
<RECEIVABLES>                                      873
<ALLOWANCES>                                      (25)
<INVENTORY>                                        547
<CURRENT-ASSETS>                                35,670
<PP&E>                                           1,724
<DEPRECIATION>                                 (1,187)
<TOTAL-ASSETS>                                  36,287
<CURRENT-LIABILITIES>                            1,197
<BONDS>                                              0
<PREFERRED-MANDATORY>                                0
<PREFERRED>                                          0
<COMMON>                                           263
<OTHER-SE>                                      34,827
<TOTAL-LIABILITY-AND-EQUITY>                    36,287
<SALES>                                          2,041
<TOTAL-REVENUES>                                 3,525
<CGS>                                            1,107
<TOTAL-COSTS>                                    7,341
<OTHER-EXPENSES>                                     0
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                   0
<INCOME-PRETAX>                                      0
<INCOME-TAX>                                         0
<INCOME-CONTINUING>                                  0
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                   (3,816)
<EPS-BASIC>                                     (0.18)
<EPS-DILUTED>                                   (0.18)