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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 HSeww4DmcJCEyN8PdPcH3q62WbsyjhjzzBhtA5QolfrHZv5/EBDO+sxtT6a7tiZp
 8iP/eJEeRf8hrzDb1cQs6Q==

<SEC-DOCUMENT>9999999997-06-018902.txt : 20060509
<SEC-HEADER>9999999997-06-018902.hdr.sgml : 20060509
<ACCEPTANCE-DATETIME>20060509162311
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ACCESSION NUMBER:		9999999997-06-018902
CONFORMED SUBMISSION TYPE:	ARS
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20051231
FILED AS OF DATE:		20060508
DATE AS OF CHANGE:		20060509
EFFECTIVENESS DATE:		20060508

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			OSI PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0000729922
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				133159796
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		ARS
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-15190
		FILM NUMBER:		06035719

	BUSINESS ADDRESS:	
		STREET 1:		41 PINELAWN ROAD
		CITY:			MELVILLE
		STATE:			NY
		ZIP:			11747
		BUSINESS PHONE:		631-962-2000

	MAIL ADDRESS:	
		STREET 1:		41 PINELAWN ROAD
		CITY:			MELVILLE
		STATE:			NY
		ZIP:			11747

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ONCOGENE SCIENCE INC
		DATE OF NAME CHANGE:	19920703
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<FILENAME>9999999997-06-018902.paper
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This document was generated as part of a paper submission.
Please reference the Document Control Number 06035719 for access to the original document.
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