424B3 1 0001.txt PROSPECTUS SUPPLEMENT RULE NO. 424(b)(3) REGISTRATION NO. 333-89355 PROSPECTUS SUPPLEMENT No. 3 (To Prospectus dated November 22, 1999) [LOGO] BIOTECH HOLDRS(SM) 1,000,000,000 Depositary Receipts Biotech HOLDRS(SM) Trust This prospectus supplement amends and supplements information contained in the prospectus dated November 22, 1999 relating to the sale of up to 1,000,000,000 depositary receipts by Biotech HOLDRS(SM) Trust. The share amounts specified in the table on page 9 of the base prospectus shall be replaced with the following:
Primary Share Trading Name of Company Ticker Amounts Market -------------------------------- ------ ------- ------- Amgen, Inc. AMGN 46 NASDAQ Genentech, Inc. DNA 22 NYSE Biogen, Inc. BGEN 13 NASDAQ Immunex Corporation IMNX 42* NASDAQ PE Corp-PE Biosystems Group PEB 18* NYSE MedImmune, Inc. MEDI 15* NASDAQ Chiron Corporation CHIR 16 NASDAQ Genzyme Corporation GENZ 7 NASDAQ Gilead Sciences, Inc. GILD 4 NASDAQ Sepracor, Inc. SEPR 6* NASDAQ IDEC Pharmaceuticals Corporation IDPH 4* NASDAQ QLT Inc.(/1/) QLTI 5 NASDAQ Millennium Pharmaceuticals, Inc. MLNM 6* NASDAQ BioChem Pharma, Inc. BCHE 9 NASDAQ Affymetrix, Inc. AFFX 2 NASDAQ Human Genome Sciences, Inc. HGSI 4* NASDAQ ICOS Corporation ICOS 4 NASDAQ Enzon, Inc. ENZN 3 NASDAQ Celera Genomics CRA 4* NYSE Alkermes, Inc. ALKS 4* NASDAQ
------- * Reflects previous stock split. (1) On May 26, 2000, QLT Photo Therapeutics, Inc. changed its name to QLT Inc. The share amounts listed in the table above reflect all previous stock splits. The stock prices in the tables set forth in Annex A of the base prospectus will not be adjusted to account for the stock splits. The date of this prospectus supplement is June 30, 2000.