-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, FLFAYzKuVQouqk4mJcBbvCpmGaS46vZF6x36wzdhQm0epCqYiUrnVKHgFeUWDExz HMDK6Iln3OV5IeYVTGnsPw== 0000947871-05-000221.txt : 20050201 0000947871-05-000221.hdr.sgml : 20050201 20050131215603 ACCESSION NUMBER: 0000947871-05-000221 CONFORMED SUBMISSION TYPE: 424B3 PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20050201 DATE AS OF CHANGE: 20050131 FILER: COMPANY DATA: COMPANY CONFORMED NAME: MERRILL LYNCH PIERCE FENNER & SMITH INC CENTRAL INDEX KEY: 0000728612 STANDARD INDUSTRIAL CLASSIFICATION: SECURITY BROKERS, DEALERS & FLOTATION COMPANIES [6211] IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 424B3 SEC ACT: 1933 Act SEC FILE NUMBER: 333-89355 FILM NUMBER: 05563684 BUSINESS ADDRESS: STREET 1: 4 WORLD FINANCIAL CENTER STREET 2: NORTH TOWER FL 12 CITY: NEW YORK STATE: NY ZIP: 10080 BUSINESS PHONE: 2124496202 MAIL ADDRESS: STREET 1: 4 WORLD FINANCIAL CENTER STREET 2: NORTH TOWER FL 12 CITY: NEW YORK STATE: NY ZIP: 10080 424B3 1 f424b3_013105-biotech.txt PROSPECTUS SUPPLEMENT PROSPECTUS SUPPLEMENT FILED PURSUANT TO RULE NO. 424(b)(3) (To Prospectus dated October 25, 2004) REGISTRATION NO. 333-89355 [BIOTECH HOLDRS(SM) TRUST LOGO OMITTED] 1,000,000,000 Depositary Receipts Biotech HOLDRS (SM) Trust This prospectus supplement supplements information contained in the prospectus dated October 25, 2004 relating to the sale of up to 1,000,000,000 depositary receipts by the Biotech HOLDRS (SM) Trust. The share amounts specified in the table in the "Highlights of Biotech HOLDRS" section of the base prospectus shall be replaced with the following:
Share Primary Name of Company Ticker Amounts Trading Market - -------------------------------------------------------- --------- --------- ----------------- Affymetrix, Inc. AFFX 4 NASDAQ Alkermes, Inc. ALKS 4 NASDAQ Amgen Inc. AMGN 64.48 NASDAQ Applera Corporation--Applied Biosystems Group* ABI 18 NYSE Applera Corporation--Celera Genomics Group* CRA 4 NYSE Biogen IDEC Inc. BIIB 26.95 NASDAQ Chiron Corporation CHIR 16 NASDAQ Enzon Pharmaceuticals, Inc. ENZN 3 NASDAQ Genentech, Inc. DNA 88 NYSE Genzyme Corporation GENZ 14 NASDAQ Gilead Sciences, Inc. GILD 32 NASDAQ Human Genome Sciences, Inc. HGSI 8 NASDAQ ICOS Corporation ICOS 4 NASDAQ MedImmune, Inc. MEDI 15 NASDAQ Millennium Pharmaceuticals, Inc. MLNM 12 NASDAQ QLT Inc. QLTI 5 NASDAQ Sepracor Inc. SEPR 6 NASDAQ Shire Pharmaceuticals Group p.l.c. SHPGY 6.8271 NASDAQ
--------------------- * The securities of this company trade as a tracking stock. Please see "Risk Factors" and the business description in Annex A for additional information relating to an investment in tracking stock. The share amounts listed in the table above reflect all previous stock splits, dividends and business combination transactions. The date of this prospectus supplement is December 31, 2004. -----END PRIVACY-ENHANCED MESSAGE-----