<SEC-DOCUMENT>0001140361-18-006056-index.html : 20180209
<SEC-HEADER>0001140361-18-006056.hdr.sgml : 20180209
<ACCEPTANCE-DATETIME>20180209121138
ACCESSION NUMBER:		0001140361-18-006056
CONFORMED SUBMISSION TYPE:	SC 13G
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20180209
DATE AS OF CHANGE:		20180209

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			OTONOMY, INC.
		CENTRAL INDEX KEY:			0001493566
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				262590070
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-88295
		FILM NUMBER:		18589922

	BUSINESS ADDRESS:	
		STREET 1:		4796 EXECUTIVE DRIVE
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		(619) 323-2200

	MAIL ADDRESS:	
		STREET 1:		4796 EXECUTIVE DRIVE
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Otonomy, Inc.
		DATE OF NAME CHANGE:	20100607

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			FIRST MANHATTAN CO
		CENTRAL INDEX KEY:			0000728083
		IRS NUMBER:				131957714
		STATE OF INCORPORATION:			NY
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G

	BUSINESS ADDRESS:	
		STREET 1:		399 PARK AVE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		2127563300

	MAIL ADDRESS:	
		STREET 1:		399 PARK AVE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G
<SEQUENCE>1
<FILENAME>doc1.htm
<DESCRIPTION>NONE
<TEXT>
Document 1 - file: doc1.htm

</DOCUMENT>
</SEC-DOCUMENT>