<SEC-DOCUMENT>0001140361-15-005315-index.html : 20150211
<SEC-HEADER>0001140361-15-005315.hdr.sgml : 20150211
<ACCEPTANCE-DATETIME>20150211104103
ACCESSION NUMBER:		0001140361-15-005315
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20150211
DATE AS OF CHANGE:		20150211

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Orexigen Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001382911
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				651178822
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-83422
		FILM NUMBER:		15597396

	BUSINESS ADDRESS:	
		STREET 1:		3344 N. TORREY PINES CT.
		STREET 2:		SUITE 200
		CITY:			LA JOLLA
		STATE:			CA
		ZIP:			92037
		BUSINESS PHONE:		(858) 875-8600

	MAIL ADDRESS:	
		STREET 1:		3344 N. TORREY PINES CT.
		STREET 2:		SUITE 200
		CITY:			LA JOLLA
		STATE:			CA
		ZIP:			92037

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			FIRST MANHATTAN CO
		CENTRAL INDEX KEY:			0000728083
		IRS NUMBER:				131957714
		STATE OF INCORPORATION:			NY
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		399 PARK AVE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		2127563300

	MAIL ADDRESS:	
		STREET 1:		399 PARK AVE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>doc1.htm
<DESCRIPTION>NONE
<TEXT>
Document 1 - file: doc1.htm

</DOCUMENT>
</SEC-DOCUMENT>