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Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Cash flows from operating activities:      
Net loss $ (16,837) $ (15,899) $ (14,399)
Adjustments to reconcile net loss to net cash used for operating activities:      
Depreciation 365 344 342
Amortization of deferred loan costs 72 42 56
Amortization of debt discount 2,372 1,918 1,937
Interest added to loan principal 3,261 2,782 2,356
Unrealized (gain) loss on derivative liability (108) 110  
Compensation charge for stock awards and share options 2,376 4,009 2,273
Issuance of stock for services     500
Changes in operating assets and liabilities:      
Decrease (increase) in accounts receivable 138 (102) (109)
(Increase) decrease in prepaid expenses and other (305) 63 145
Decrease in other assets 63 220 194
Increase (decrease) in accounts payable 304 (141) 252
Increase (decrease) in accrued liabilities 285 (107) (30)
Increase in tax liability     105
Increase in deferred revenue 500    
Net cash used for operating activities (7,514) (6,761) (6,378)
Cash flows from investing activities:      
Additions to property, plant and equipment (4,140) (1,184) (119)
Proceeds from sale of marketable securities     4,500
Net cash (used for) provided by investing activities (4,140) (1,184) 4,381
Cash flows from financing activities:      
Net proceeds from issuance of common stock 15,129   8,835
Proceeds from issuance of long-term debt 2,000 5,000 46
Principal payments on long-term debt (16) (22) (20)
Net cash provided by financing activities 17,113 4,978 8,861
Net increase (decrease) in cash and cash equivalents 5,459 (2,967) 6,864
Cash and cash equivalents, beginning of period 5,911 8,878 2,014
Cash and cash equivalents, end of period $ 11,370 $ 5,911 $ 8,878