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Supplemental Data (Unaudited)
 12 Months Ended
Dec. 31, 2017
Quarterly Financial Information Disclosure [Abstract]  
Supplemental Data (Unaudited)

The following is a summary of unaudited selected quarterly financial information for the three months ended (in thousands, except per share data):
 
December 31,
September 30,
June 30,
March 31,
 
2017
2017
2017
2017
Revenue
$
2,120

$
828

$
699

$
530

Gross profit
$
1,470

$
637

$
564

$
504

Loss from operations
$
(16,136
)
$
(17,315
)
$
(16,423
)
$
(14,310
)
Net loss
$
(16,296
)
$
(17,075
)
$
(16,457
)
$
(14,200
)
Basic and diluted net loss per share
$
(0.29
)
$
(0.31
)
$
(0.31
)
$
(0.27
)

 
December 31,
September 30,
June 30,
March 31,
 
2016
2016
2016
2016
Revenue
$
39

$
24

$
20

$
163

Gross profit
$
39

$
24

$
20

$
163

Loss from operations
$
(16,024
)
$
(17,416
)
$
(17,889
)
$
(15,172
)
Net loss
$
(16,135
)
$
(17,299
)
$
(17,866
)
$
(15,074
)
Basic and diluted net loss per share
$
(0.31
)
$
(0.34
)
$
(0.35
)
$
(0.29
)