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CONDENSED CONSOLIDATED STATEMENT OF CASH FLOWS - USD ($)
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Cash flows from operating activities:    
Net loss $ (14,200,000) $ (15,074,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 505,000 542,000
Amortization of intangible assets 3,000 3,000
Amortization of investment discount 121,000 37,000
Equity-based compensation 3,215,000 1,686,000
(Increase) decrease in assets:    
Accounts receivable (522,000) 0
Inventory (4,155,000) 0
Prepaid expense and other (457,000) (518,000)
Other current assets (280,000) (1,212,000)
Increase (decrease) in liabilities:    
Accounts payable 276,000 494,000
Accrued liabilities (4,000) 906,000
Deferred revenue and income 29,000 (69,000)
Net cash used in operating activities (15,469,000) (13,205,000)
Cash flows from investing activities:    
Purchases of equipment (229,000) (1,681,000)
Purchases of available-for-sale securities (4,562,000) (36,718,000)
Sales of available-for-sale securities 0 500,000
Maturity of available-for-sale securities 8,845,000 3,400,000
Net cash provided (used) in investing activities 4,054,000 (34,499,000)
Cash flows from financing activities:    
Issuance of common stocks 189,000 0
Exercise of options and warrants 1,844,000 28,000
Common stock issuance costs 0 (814,000)
Payments on capital lease obligations 0 (13,000)
Net cash provided (used) by financing activities 2,033,000 (799,000)
Effect of exchange rate on cash: 55,000 (49,000)
Decrease in cash and cash equivalents (9,327,000) (48,552,000)
Cash and cash equivalents, beginning of period 19,244,000 120,585,000
Cash and cash equivalents, end of period $ 9,917,000 $ 72,033,000