HART & TRINEN, LLP
                                ATTORNEYS AT LAW
                             1624 Washington Street
                                Denver, CO 80203
William T. Hart, P.C.              ________           Email:  harttrinen@aol.com
Donald T. Trinen                                      Facsimile:  (303) 839-5414
                                 (303) 839-0061

                                October 19, 2009

Rose Zukin
Mailstop 4720
Securities and Exchange Commission
100 F Street, NE
Washington, DC 20549

      Re:   Cel-Sci Corporation
            Registration Statement on Form S-3
            File No. 333-161504


     This office represents Cel-Sci Corporation (the "Company"). Amendment No. 2
to the  Company's  Registration  Statement  on Form S-3 has been  filed with the
Commission.  This  letter  provides  the  Company's  responses  to the  comments
received from the Staff by letter dated October 7, 2009.  The paragraph  numbers
in this letter  correspond  with the numbered  paragraphs in the Staff's comment
letter.  The number under the "Page Number" column  indicates the page number in
the S-3 Registration Statement where the response to the comment can be found.

                                                                        Page #
                                                                        ------

     1.   Comment complied with.                                        17, 18

     2.   Comment complied with.                                            17



                                          Very Truly Yours,

                                          HART & TRINEN, L.L.P.


                                          By:  /s/ William T. Hart

                                               William T. Hart

WTH:tg