EXHIBIT 5





                               September 28, 2009

CEL-SCI Corporation
8229 Boone Blvd., Suite 802
Vienna, Virginia 22182

     This letter will constitute an opinion upon the legality of the sale by
CEL-SCI Corporation, a Colorado corporation, of up to 32,000,000 shares of
Common Stock, all as referred to in the Registration Statement on Form S-8 filed
by the Company with the Securities and Exchange Commission.

         We have examined the Articles of Incorporation, the Bylaws and the
minutes of the Board of Directors of the Company and the applicable laws of the
State of Colorado, and a copy of the Registration Statement. In our opinion, the
Company has duly authorized the issuance of the shares of stock mentioned above
and such shares when sold, will be legally issued, fully paid, and
nonassessable.

                                Very truly yours,

                                  HART & TRINEN


                             By /s/ William T. Hart
                                 William T. Hart