-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 RWf4uypvGF86b7+xxrkqElnOGhbSfLNk24LItlzaImapCQnJ6Xl+LotTAaiEn0FO
 eoKzbQWpkVOd6FXtiOEOqQ==

<SEC-DOCUMENT>0000725058-03-000018.txt : 20030613
<SEC-HEADER>0000725058-03-000018.hdr.sgml : 20030613
<ACCEPTANCE-DATETIME>20030613161723
ACCESSION NUMBER:		0000725058-03-000018
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20030611
FILED AS OF DATE:		20030613

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			REISER H JOSEPH
		CENTRAL INDEX KEY:			0001211251

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-14879
		FILM NUMBER:		03743922

	MAIL ADDRESS:	
		STREET 1:		650 COLLEDGE ROAD EAST
		STREET 2:		SUITE 3100
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08540-5308

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CYTOGEN CORP
		CENTRAL INDEX KEY:			0000725058
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				222322400
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		600 COLLEGE RD EAST CN 5308
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08540
		BUSINESS PHONE:		6099878200

	MAIL ADDRESS:	
		STREET 1:		600 COLLEGE RD EAST CN 5308
		STREET 2:		600 COLLEGE RD EAST CN 5308
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08540
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>reiser_form4ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<!-- - EDGAR Ease Plus 1.0                                   04/22/03  TZ    -->
<ownershipDocument>
    <schemaVersion>X0101</schemaVersion>

    <documentType>4</documentType>
   <periodOfReport>2003-06-11</periodOfReport>
    <issuer>
        <issuerCik>0000725058</issuerCik>
        <issuerName>CYTOGEN CORP</issuerName>
        <issuerTradingSymbol>CYTO</issuerTradingSymbol>
   </issuer>
   <reportingOwner>
      <reportingOwnerId>
            <rptOwnerCik>0001211251</rptOwnerCik>
            <rptOwnerName>REISER H JOSEPH</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>  </rptOwnerStreet1>
            <rptOwnerStreet2>  </rptOwnerStreet2>
            <rptOwnerCity>  </rptOwnerCity>
            <rptOwnerState>  </rptOwnerState>
            <rptOwnerZipCode>  </rptOwnerZipCode>
        </reportingOwnerAddress>
            <reportingOwnerRelationship>
         <isDirector>1</isDirector>
         <isOfficer>0</isOfficer>
         <isTenPercentOwner>0</isTenPercentOwner>
         <isOther>0</isOther>
       </reportingOwnerRelationship>
   </reportingOwner>
   <derivativeSecurity>
      <securityTitle>
         <value>Common Stock Option (right to buy)</value>
      </securityTitle>
      <conversionOrExercisePrice>
         <value>5.84</value>
      </conversionOrExercisePrice>
      <transactionDate>
         <value>2003-06-11</value>
      </transactionDate>
      <transactionCoding>
         <transactionFormType>4</transactionFormType>
         <transactionCode>A</transactionCode>
         <equitySwapInvolved>0</equitySwapInvolved>
      </transactionCoding>
      <transactionAmounts>
         <transactionShares>
           <value>1000</value>
         </transactionShares>
         <transactionValue>
           <value>0</value>
         </transactionValue>
         <transactionAcquiredDisposedCode>
           <value>A</value>
         </transactionAcquiredDisposedCode>
      </transactionAmounts>
      <exerciseDate>
         <value>2004-06-11</value>
            <footnoteId id="F1"/>
      </exerciseDate>
      <expirationDate>
         <value>2013-06-11</value>
      </expirationDate>
      <underlyingSecurity>
         <underlyingSecurityTitle>
           <value>Common Stock</value>
         </underlyingSecurityTitle>
         <underlyingSecurityShares>
           <value>1000</value>
         </underlyingSecurityShares>
      </underlyingSecurity>
      <postTransactionAmounts>
         <sharesOwnedFollowingTransaction>
           <value>1000</value>
         </sharesOwnedFollowingTransaction>
      </postTransactionAmounts>
      <ownershipNature>
         <directOrIndirectOwnership>
           <value>D</value>
         </directOrIndirectOwnership>
      </ownershipNature>
   </derivativeSecurity>
   <footnotes>
<footnote id="F1"> These options vest 100% after one year from the date of grant.</footnote>
   </footnotes>
   <ownerSignature>
      <signatureName>H. Joseph Reiser</signatureName>
      <signatureDate>2003-06-13</signatureDate>
   </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----