Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Revenue:
Revenue	$ 4,159	$ 5,839
Operatingexpenses:
Research and development	17,275	12,355
General and administrative	6,681	3,499
Impairment of intangible assets	1,600
Costs of exit from leased premises	359
Total operating expenses	25,915	15,854
Operating loss	(21,756)	(10,015)
Other income and (expenses):
Bargain purchase gain	6,760
Interest income	58	53
Interest expense	(821)	(3,036)
Non-cash interest expense related to sale of future royalties	(1,859)
(Loss) gain on sale of equipment	(11)	69
(Loss) gain on revaluation of financial instruments, net	(3)	3,347
Foreign exchange loss, net	(266)
Total other income and (expenses)	3,858	433
Net loss before provision for income taxes	(17,898)	(9,582)
Provision for income taxes	109
Net loss	(18,007)	(9,582)
Series B and C preferred dividend	(339)	(2,878)
Net comprehensive loss attributable to common stockholders	$ (18,346)	$ (12,460)
Net loss per share – basic and diluted (in Dollars per share)	$ (2.90)	$ (91.65)
Shares used to compute net loss per share – basic and diluted (in Shares)	6,316,065	135,953
Government Contract [Member]
Revenue:
Revenue	$ 1,344	$ 5,839
Royalty [Member]
Revenue:
Revenue	1,340
Non Cash Royalty Revenue [Member]
Revenue:
Revenue	$ 1,475