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Note 1 - Organization and Nature of Business (Details Textual)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended
Sep. 15, 2021
USD ($)
Jan. 31, 2024
USD ($)
$ / shares
shares
Mar. 31, 2024
USD ($)
$ / shares
shares
Mar. 31, 2023
USD ($)
Number of Reportable Segments     1  
RA Capital Healthcare Fund 2024 [Member]        
Stock Issued During Period, Shares, New Issues (in shares) | shares   15,384,615 15,384,615  
Shares Issued, Price Per Share (in dollars per share) | $ / shares   $ 0.65 $ 0.65  
Gross Proceeds from Issuance of Common Stock   $ 10,000 $ 10,000  
Net Proceeds From Issuance of Common Stock   $ 9,900 9,900  
Proceeds from Issuance of Common Stock     $ 9,945 $ 0
The September 2021 ATM [Member]        
Stock Issued During Period, Shares, New Issues (in shares) | shares     7,404,672  
Open Market Sale Agreement, Maximum Aggregate Offering Price $ 100,000      
Open Market Sale Agreement, Sales Commission, Percentage 3.00%      
Proceeds from Issuance of Common Stock     $ 8,700  
Proceeds from Issuance of Common Stock, Net     $ 8,400