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Note 19 - Quarterly Financial Data (Unaudited) (Tables)
 12 Months Ended
Dec. 31, 2020
Notes Tables  
Quarterly Financial Information [Table Text Block]
   
Year Ended December 31, 2020
  
   
First
    
Second
    
Third
    
Fourth
  
                                 
Revenue
   $
2,902
     $
523
     $
265
     $
356
  
Operating expenses
   $
3,596
     $
9,049
     $
7,854
     $
13,717
  
Net loss
   $
(1,297
 )   $
(8,977
 )   $
(8,085
 )   $
(13,861
 )
Net loss per share – basic and diluted
   $
(0.02
 )   $
(0.12
 )   $
(0.08
 )   $
(0.13
 )
   
Year Ended December 31, 2019
  
   
First
    
Second
    
Third
    
Fourth
  
                                 
Revenue
   $
5,407
     $
85
     $
454
     $
3,916
  
Operating expenses
   $
5,855
     $
5,082
     $
5,168
     $
9,542
  
Net loss
   $
(1,339
 )   $
(5,637
 )   $
(5,260
 )   $
(6,409
 )
Net loss per share – basic and diluted
   $
(0.18
 )   $
(0.39
 )   $
(0.32
 )   $
(0.13
 )
   
Year Ended December 31, 2018
  
   
First
    
Second
    
Third
    
Fourth
  
                                 
Revenue
   $
1,503
     $
608
     $
281
     $
1,767
  
Operating expenses
   $
5,418
     $
8,383
     $
6,161
     $
5,953
  
Net income (loss)
   $
2,314
     $
(8,871
 )   $
(6,548
 )   $
(4,902
 )
Net income (loss) attributable to common stockholders
   $
1,975
     $
(8,871
 )   $
(6,548
 )   $
(4,902
 )
Net income (loss) per share – basic
   $
0.54
     $
(1.24
 )   $
(0.92
 )   $
(0.69
 )
Net income (loss) per share – diluted
   $
0.49
     $
(1.24
 )   $
(0.92
 )   $
(0.69
 )