Note 5 - Balance Sheet Components (Tables)

12 Months Ended

Dec. 31, 2019

Notes Tables

Schedule of Cash and Cash Equivalents [Table Text Block]

	December 31, 2019		December 31, 2018
	(in thousands)
Cash at banks	$	13,511	$	11,441
Restricted cash		—		50
Money market funds		15		15
Cash and cash equivalents	$	13,526	$	11,506

Schedule of Accounts, Notes, Loans and Financing Receivable [Table Text Block]

	December 31, 2019		December 31, 2018
	(in thousands)
Royalties receivable	$	3,438	$	1,776
Customer service contracts – billed		181		—
Government contract – billed		—		20
Accounts receivable	$	3,619	$	1,796

Property, Plant and Equipment [Table Text Block]

	December 31, 2019			December 31, 2018
	(in thousands)
Laboratory equipment	$	537		$	2,076
Office and computer equipment		132			227
Leasehold improvements		—			333
Total property and equipment		669			2,636
Less: accumulated depreciation		(459	)		(1,570	)
Property and equipment, net	$	210		$	1,066

Lessee, Operating Lease, Right-of-Use Assets [Table Text Block]

	December 31, 2019
	(in thousands)
Facilities	$	1,985
Office equipment		5
Right-of-use assets, net	$	1,990

Schedule of Finite-Lived Intangible Assets [Table Text Block]

	December 31, 2019			December 31, 2018
	(in thousands)
Purchased technology	$	22,100		$	22,100
Intellectual property		80			80
Total cost		22,180			22,180
Less accumulated amortization		(5,087	)		(2,767	)
Intangible assets, net	$	17,093		$	19,413

Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]

Year Ending December 31,	Amount
2020	$	1,732
2021		1,732
2022		1,732
2023		1,731
2024		1,732
Thereafter		8,434
Total	$	17,093

Schedule of Accrued Liabilities [Table Text Block]

	December 31, 2019		December 31, 2018
	(in thousands)
Accrued compensation	$	903	$	632
Accrued clinical and manufacturing expenses		3,228		75
Accrued professional and consulting services		2		166
Reserve for return of royalties		178		339
Deferred rent and lease loss accrual, current portion		—		111
Other		254		195
Total	$	4,565	$	1,518