FORM 4      Check this box if no longer 
     subject to Section 16. Form 4
     or Form 5 obligations may 
     continue. See Instruction 1(b).      (Print or Type Responses) UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility
Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940 OMB APPROVAL
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1.  Name and Address of Reporting Person*      Tolkowsky Dan	2.  Issuer Name and Tickler or Trading Symbol Bio-Technology General Corp.: ("BTGC")					6.  Relationship of Reporting Person(s) to Issuer          (Check all applicable)     X     Director                                      10% Owner          Officer (give title below)            Other (specify below)
(Last)     (First)     (Middle) 6 Hadassah Street, Apt. 181	3. I.R.S. Identification     Number of Reporting     Person, if an entity     (voluntary)		4.  Statement for Month//Day/Year        March 31, 2003
(Street) Tel Aviv   Israel  64513			5.  If Amendment, Date of  Original (Month/Day/Year)			7.  Individual or Joint/Group Filing (Check Applicable Line)     X Form filed by One Reporting Person         Form filed by More than One Reporting Person
(City)     (State)     (Zip)	Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.  Title of Security    (Instr. 3)	2.  Transaction Date (Month/Day/Year)	2A.  Deemed        Execution Date,        if any   (Month/Day/Year)	3. Transaction Code    (Instr. 8)		4. Securities  Acquired  (A)     or Disposed of (D)     (Instr. 3, 4 and 5)			5.  Amount of Securities     Beneficially Owned     Following Reported     Transaction(s)     (Instr. 3 and 4)	6.  Ownership      Form: Direct      (D) or      Indirect (I)      (Instr. 4)	7.  Nature of     Indirect     Beneficial     Ownership     (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock, $.01 par value per share	03/31/2003		A		925 (1)	A	$2.70	62,325	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)

1.Title of    Derivative    Security    (Instr.3) Options to purchase Common Stock, $.01 par value per share

2.Conversion or  Exercise Price of  Derivative Security

3.Transaction Date (Month/Day/Year)

3A.  Deemed Execution Date, if any (Month/Day/Year)

4.Transaction Code    (Instr. 8)

5.Number of Derivative    Securities Acquired    (A) or Disposed of (D)    (Instr. 3, 4 and 5)

6.Date Exerciseable    and Expiration  Date   (Month/Day/Year)

7.Title and  Amount of    Underlying Securities    (Instr. 3 and 4)   Common Stock, $.01 par value per share

8.Price of    Derivative    Security    (Instr. 5)

9.Number  of    Derivative    Securities    Beneficially    Owned    Following    Reported    Transaction(s)     (Instr. 4)

10.Ownership      Form of      Derivative      Securities      Beneficially      Owned at      End of Month      (Instr. 4)

11.Nature  of      Indirect      Beneficial      Ownership      (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

"      "

$14.125

6/18/97

A

7,500

(2)

6/18/07

"

7,500

D

"      "

$7.875

6/17/98

A

7,500

(2)

6/17/08

"

7,500

D

"      "

$7.40625

6/9/99

A

7,500

(2)

6/9/09

"

7,500

D

"      "

$11.8125

9/6/00

A

7,500

(3)

9/6/10

"

7,500

D

"      "

$12.74

6/19/01

A

7,500

(4)

6/19/11

"

7,500

D

"      "

$4.91

3/29/02

A

5,000

(2)

3/29/12

"

5,000

D

"      "

$6.01

6/28/02

A

5,000

(5)

6/28/12

"

5,000

D

"      "

$2.961

9/30/02

A

5,000

(6)

9/30/12

"

5,000

D

"      "

$3.201

12/31/02

A

5,000

(7)

12/31/02

"

5,000

D

"      "

$2.70

3/31/03

A

5,000

(8)

3/31/13

"

5,000

62,500

D

Explanation of Responses:   1. These shares were granted pursuant to the Company's Stock Compensation Plan for Outside Directors, which provides for the grant to no-employee directors of that number of shares of Common Stock having an aggregate fair market value on the last business day of each quarter equal to $2,500, until he is no longer an Outside Director.  On March  31, 2003, the fair market value of the Common Stock, based on the closing price, was $2.70.  2.  These options are fully vested and immediately exercisable.   3.  These options are presently exercisable as to 5,625 shares and will become exercisable as to an additional 1,875 shares on 9/6/03.   4.  These options are presently exercisable as to 3,750 shares and will become exercisable as to an additional 1,875 shares on each of 6/19/03 and 6/19/04.   5.  These options will become fully vested and immediately exercisable on 6/28/03.   6.  These options will become fully vested and immediately exercisable on 9/30/03.   7.  These options will become fully vested and immediately exercisable on 12/31/03.   8.  These options will become fully vested and immediately exercisable on 3/31/04.
		/s/ Dan Tolkowsky             **Signature of Reporting Person	April 2, 2003                 Date
Reminder:	Report on a separate line for each class of securities beneficially owned directly or indirectly.
*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:	File three copies of this Form, on of which must be manually signed. If space is insufficient, see Instruction 6 for procedure