CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2013	Mar. 31, 2012
Revenues:
Product sales, net	$ 4,692	$ 3,534
Cost and expenses:
Cost of goods sold	3,550	1,720
Research and development	6,134	7,246
Selling, general and administrative	15,156	24,252
Operating Expenses, Total	24,840	33,218
Operating loss	(20,148)	(29,684)
Investment income, net	33	43
Interest expense on debt	(7,079)	(4,557)
Other income, net	506
Loss before income taxes	(26,688)	(34,198)
Income tax benefit	2,242
Net loss	$ (24,446)	$ (34,198)
Loss per common share:
Basic and diluted	$ (0.34)	$ (0.49)
Weighted-average number of common and common equivalent shares:
Basic and diluted	71,667	70,470