CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012	Sep. 30, 2011
Revenues:
Product sales, net	$ 4,916	$ 2,581	$ 13,076	$ 5,855
Cost and expenses:
Cost of goods sold	4,222	4,584	12,669	6,008
Research and development	6,796	5,858	20,747	17,315
Selling, general and administrative	20,427	22,268	72,006	62,761
Operating Expenses, Total	31,445	32,710	105,422	86,084
Operating loss	(26,529)	(30,129)	(92,346)	(80,229)
Investment income, net	41	39	125	107
Interest expense on debt	(6,805)	(3,535)	(16,962)	(11,842)
Gain on extinguishment of debt			21,800
Other (expense) income, net	(6,408)	(12)	(2,895)	1,738
Loss before income taxes	(39,701)	(33,637)	(90,278)	(90,226)
Income tax benefit		(6,245)		(19,055)
Net loss	$ (39,701)	$ (27,392)	$ (90,278)	$ (71,171)
Loss per common share:
Basic and diluted	$ (0.56)	$ (0.39)	$ (1.28)	$ (1.02)
Weighted-average number of common shares:
Basic and diluted	70,956	70,122	70,718	70,037