Commitments and Contingencies - Additional Information (Detail) (USD $)	1 Months Ended			3 Months Ended		6 Months Ended
	May 31, 2010	Nov. 30, 2008	May 31, 2007	Jun. 30, 2012	Jun. 30, 2011	Jun. 30, 2012 Year Month Employee	Jun. 30, 2011	Jan. 23, 2012 sqft
Commitments and Contingencies Disclosure [Line Items]
Plan of reorganization, annual operating expenses to be reduce by 2013						$ 54,000,000
Non-cash charge to cost of goods sold				4,900,000
Potential commitment of retention awards						200,000
Number of senior officers with employment agreements						8
Annual employee benefits compensation committed						3,000,000
Number of years employment agreement renewed, period						One
Severance agreements, aggregate amount				400,000		400,000
Severance expense						600,000
Term of employment agreement, in years						3
Retention awards vesting percentage of award on specific dates						50.00%
Award vesting period, years						2 years
Rentable square feet of office facilities								48,000
New lease term, months						123
Number of lease renewal options						2
Number of years lease agreement, renewal option						5
Aggregate minimum lease commitment				15,200,000		15,200,000
Letter of credit to secure obligations under lease						1,600,000
Tenant improvement allowance						2,000,000
Rent expense from operations				900,000	500,000	1,600,000	1,000,000
Tax assessment	1,700,000		1,200,000
Increase in tax assessment due to additional interest and penalties	500,000
Settlement including penalty and interest						327,000
Consideration payment per Consulting Agreement						20,000
Number of clinical trials		3
During 2012
Commitments and Contingencies Disclosure [Line Items]
Potential commitment of retention awards						1,100,000
During 2013
Commitments and Contingencies Disclosure [Line Items]
Potential commitment of retention awards						1,100,000
During 2013 | Retention Agreement
Commitments and Contingencies Disclosure [Line Items]
Potential commitment of retention awards						900,000
During 2014
Commitments and Contingencies Disclosure [Line Items]
Potential commitment of retention awards						$ 900,000