Share-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2012

Schedule of Stock-Based Compensation by Expense Category

ended June 30, 2012 and 2011 was $4.0 million and $3.5 million, respectively The following table summarizes the components of share-based compensation expense in the consolidated statements of operations for the three and six-month periods ended June 30, 2012 and 2011:

	Three Months Ended June 30,				Six Months Ended June 30,
	2012		2011		2012		2011
	(In thousands)
Research and development	$	507	$	383	$	758	$	726
Selling, general and administrative		2,255		1,495		3,222		2,820
Total non-cash compensation expense related to share-based compensation included in operating expense	$	2,762	$	1,878	$	3,980	$	3,546

Schedule of Unvested Stock Option Awards

The following table summarizes the activity related to the Company’s restricted stock and RSU’s for the six-month period ended June 30, 2012:

	Number of Shares			Weighted-Average Grant Date Fair Value Per Share
	(Shares in thousands)
Unvested at December 31, 2011		811		$	8.75
Granted		1,597			1.87
Vested		(180	)		9.45
Forfeited		(264	)		8.57
Unvested at June 30, 2012		1,964		$	3.12

Stock Option

Schedule of Weighted-Average Key Assumptions Used in Determining Fair Value of Stock Option Awards

The weighted-average key assumptions used in determining the fair value of stock options granted for the three and six-month periods ended June 30, 2012 and 2011 were as follows:

	Three Months Ended June 30,						Six Months Ended June 30,
	2012			2011			2012			2011
Weighted-average volatility		95	%		100	%		94	%		92	%
Weighted-average risk-free interest rate		0.8	%		2.5	%		1.0	%		2.5	%
Weighted-average expected life in years		4.9			3.7			5.4			3.7
Dividend yield		0.0	%		0.0	%		0.0	%		0.0	%
Weighted-average grant date fair value per share	$	0.60		$	6.57		$	1.27		$	6.27

Schedule of Stock Option Activity

The following table summarizes the activity related to the Company’s stock options for the six-month period ended June 30, 2012:

	Number of Shares			Weighted- Average Exercise Price Per Share		Weighted- Average Remaining Contractual Term (in yrs)		Aggregate Intrinsic Value of In-the- Money Options
	(In thousands, except weighted-average data)
Outstanding at December 31, 2011		3,648		$	7.98		7.81	$	—
Granted		1,196			1.74		—		—
Exercised					—		—		—
Cancelled		(740	)		8.88		—		—
Outstanding at June 30, 2012		4,104		$	6.05		7.96	$
Exercisable at June 30, 2012		1,782		$	7.28		6.40	$	—

Stock Options That Contain Performance And Market-Based Conditions

Schedule of Stock Option Activity

The following table summarizes the activity related to the Company’s performance options for the six-month period ended June 30, 2012:

	Number of Shares			Weighted- Average Exercise Price Per Share		Weighted- Average Remaining Contractual Term (in yrs)		Aggregate Intrinsic Value of In-the-Money Options
	(In thousands, except weighted-average data)
Outstanding at December 31, 2011		440		$	9.75		9.07	$	—
Granted		—			—		—		—
Exercised		—			—		—		—
Cancelled		(250	)		9.23		—		—
Outstanding at June 30, 2012		190		$	10.43		8.55	$	—
Exercisable at June 30, 2012		40		$	13.81		7.42	$	—

Non-Vested Stock Option Awards

Schedule of Non-Vested Stock Option Awards That Contain Performance or Market Conditions

The following table summarizes the activity related to the Company’s performance awards for the six-month period ended June 30, 2012:

	Number of Shares			Weighted- Average Grant Date Fair Value Per Share
	(Shares in thousands)
Unvested at December 31, 2011		306		$	9.44
Granted		—			—
Vested		—			—
Forfeited		(300	)		9.23
Unvested at June 30, 2012		6		$	20.59