Consolidated Statements Of Operations (USD $) In Thousands, except Per Share data, unless otherwise specified	12 Months Ended
	Dec. 31, 2011	Dec. 31, 2010	Dec. 31, 2009
Revenues:
Product sales, net	$ 9,565	$ 4,028	$ 2,956
Other revenues			4
Total revenues	9,565	4,028	2,960
Cost and expenses:
Cost of goods sold	9,313	2,673	1,606
Research and development	24,790	32,358	51,726
Selling, general and administrative	90,898	24,981	30,790
Operating expenses	125,001	60,012	84,122
Operating loss	(115,436)	(55,984)	(81,162)
Investment income, net	150	116	289
Interest expense on Convertible Notes	(15,737)
Other income (expense), net	2,208	(17,250)	(12,051)
Loss before income taxes	(128,815)	(73,118)	(92,924)
Income tax benefit	(26,788)	(9)	(2,071)
Net loss	$ (102,027)	$ (73,109)	$ (90,853)
Loss per common share:
Basic and diluted	$ (1.46)	$ (1.08)	$ (1.51)
Weighted-average number of common and common equivalent shares:
Basic and diluted	70,117	67,435	59,997