Income Taxes - Narrative (Details) - USD ($) $ in Millions	3 Months Ended	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Income Taxes [Line Items]
Tax benefit		$ (465)	$ (419)	$ (130)
Valuation allowance		278	228
New tax benefit recognized due to change in corporate tax rate		53	23	0
NOL carryforwards, foreign		11
Intangibles		1,458	1,287
Deferred tax liabilities, intangible assets		158	147
Unrecognized tax benefits	$ 1,037	1,289	1,166	1,037	$ 926
Unrecognized tax benefits that would affect effective tax rate		784
Accrued interest and penalties related to uncertain tax positions	72	102	93	72
Interest expense related to uncertain tax positions		11	19	14
State
Income Taxes [Line Items]
Tax credit carryforward		263
R&D Credit
Income Taxes [Line Items]
Valuation allowance		118	107
UK IP Onshoring
Income Taxes [Line Items]
Tax benefit	230
Net Deferred tax asset related to the amortizable tax basis in transferred intellectual property	1,100			1,100
Deferred tax liabilities, domestic tax on foreign earnings	920			920
Valuation allowance	$ 110			$ 110
New tax benefit recognized due to change in corporate tax rate		53
Intangibles		1,200
UK IP Onshoring | Minimum
Income Taxes [Line Items]
Amortizable tax basis, recovery period				3 years
UK IP Onshoring | Maximum
Income Taxes [Line Items]
Amortizable tax basis, recovery period				25 years
US IP Onshoring
Income Taxes [Line Items]
Tax benefit			$ 31
U.S.
Income Taxes [Line Items]
Deferred tax liabilities, intangible assets		$ 989