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COMMITMENTS AND CONTINGENCIES (Details Narrative) - USD ($)
1 Months Ended 12 Months Ended
May 04, 2020
Oct. 01, 2019
Jul. 07, 2019
Aug. 27, 2018
Mar. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Feb. 11, 2021
Loss Contingencies [Line Items]                  
Royalties payable           $ 201,000      
Royalty expense           $ 856,755 $ 479,809    
Royalty percentage           2.00%      
Maximum amount of royalty                 $ 800,000
Payment for royalties           $ 50,250      
Cash $ 500,000                
Net income           (71,881) (88,705)    
2009 [Member] | Resorbable Bone Hemostat [Member]                  
Loss Contingencies [Line Items]                  
Royalties payable           $ 201,000      
Royalty percentage           3.00%      
Annual royalty obligation           $ 16,080      
Wound Care Solutions Limited [Member] | 2009 [Member]                  
Loss Contingencies [Line Items]                  
Net income         $ 200,000   200,000 $ 200,000  
Sub License Agreement [Member]                  
Loss Contingencies [Line Items]                  
Net sales description       On August 27, 2018, the Company entered into an exclusive, world-wide sublicense agreement with CGI Cellerate RX to distribute CellerateRX Surgical and HYCOL products into the wound care and surgical markets. The Company pays royalties of 3-5% of annual collected net sales of CellerateRX Surgical and HYCOL. As amended, the term of the sublicense extends through May 2050, with automatic year-to-year renewal terms thereafter so long as the Company’s Net Sales (as defined in the sublicense agreement) each year are equal to or in excess of $1,000,000. If the Company’s Net Sales fall below $1,000,000 for any year after the initial expiration date, CGI Cellerate RX will have the right to terminate the sublicense agreement upon written notice          
Royalties payable       $ 400,000          
BIAKOS License Agreement [Member]                  
Loss Contingencies [Line Items]                  
Royalty expense           $ 110,000 $ 100,000    
BIAKOS License Agreement [Member] | Rochal Industries LLC [Member] | Minimum [Member]                  
Loss Contingencies [Line Items]                  
Royalty percentage     2.00%            
BIAKOS License Agreement [Member] | Rochal Industries LLC [Member] | Maximum [Member]                  
Loss Contingencies [Line Items]                  
Royalty percentage     4.00%            
BIAKOS Agreement [Member]                  
Loss Contingencies [Line Items]                  
Royalty annual minimum percentage   10.00%              
Payment for royalties     $ 1,000,000            
BIAKOS Agreement [Member] | Rochal Industries LLC [Member]                  
Loss Contingencies [Line Items]                  
Royalties payable     100,000            
Maximum amount of royalty     $ 150,000            
ABF License Agreement [Member]                  
Loss Contingencies [Line Items]                  
Royalties payable   $ 50,000              
Royalty annual minimum percentage   10.00%              
Maximum amount of royalty   $ 75,000              
Payment for royalties   $ 500,000              
ABF License Agreement [Member] | Minimum [Member]                  
Loss Contingencies [Line Items]                  
Royalty percentage   2.00%              
ABF License Agreement [Member] | Maximum [Member]                  
Loss Contingencies [Line Items]                  
Royalty percentage   4.00%              
Debrider License Agreement [Member]                  
Loss Contingencies [Line Items]                  
Royalty annual minimum percentage 10.00%                
Maximum amount of royalty $ 150,000                
Payment for royalties 1,000,000                
Cash 600,000                
Payable of common stock $ 1,000,000                
Debrider License Agreement [Member] | Minimum [Member]                  
Loss Contingencies [Line Items]                  
Royalty percentage 2.00%                
Debrider License Agreement [Member] | Maximum [Member]                  
Loss Contingencies [Line Items]                  
Royalty percentage 4.00%