8-K

                       SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON D.C. 20549


                                   ----------


                                    FORM 8-K


                                 CURRENT REPORT
                                   PURSUANT TO
                             SECTION 13 OR 15(D) OF
                       THE SECURITIES EXCHANGE ACT OF 1934


       DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED): November 21, 2000


                                 MEDIA 100 INC.
               (Exact name of Registrant as specified in charter)

        DELAWARE                 0-14779                     04-2532613
    (State or other         (Commission File              (I.R.S. Employer
      jurisdiction)              Number)                 Identification No.)


             290 DONALD LYNCH BOULEVARD, MARLBOROUGH, MA 01752-4748
              (Address of Principal Executive Offices) (Zip Code)


                                 (508) 460-1600
                Registrant's Telephone number including area code


ITEM 5.  OTHER EVENTS.

On November 21, 2000, the Registrant issued a press release announcing lower
revenue and earnings expectations for its fourth fiscal quarter ending November
30, 2000 and provided revenue and earnings guidance for the next fiscal year
ending November 30, 2001. Reference is made to the press release which is
included as Exhibit 99.

ITEM 7.  FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS.

         (c)      EXHIBITS.

Exhibit Number    Title

99                Press Release of the Registrant dated November 21, 2000.

                                   SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                       MEDIA 100 INC.


                                       By /s/ Steven Shea
Date:  November 29, 2000               Steven Shea
                                       Chief Financial Officer and Treasurer


                                  EXHIBIT INDEX


Exhibit Number    Description

99                Press Release of the Registrant dated November 21, 2000.

EX-99

[media logo]

PRESS RELEASE
FOR IMMEDIATE RELEASE

PRESS/INVESTOR CONTACTS:
Kevin Bourke                                     Evan Smith/Jennifer Hendrickson
Media 100 Inc.                                   Shandwick International
(508) 303-4825                                   (646) 658-8123/ (646) 658-8240
kbourke@media100.com                             evsmith@shandwick.com
                                                 jhendrickson@shandwick.com


               MEDIA 100 LOWERS EARNINGS AND REVENUE EXPECTATIONS
                         FOR ITS FOURTH FISCAL QUARTER

MARLBORO, MA (NOVEMBER 21, 2000) -- Media 100 Inc. (NASDAQ:MDEA), the leading
provider of software, systems and services for streaming media on the Internet,
today announced reduced revenue and earnings expectations for its fourth quarter
ending November 30, 2000. The Company expects to report a loss of approximately
$0.09 to $0.10 per share, excluding charges, on revenue of approximately
$16,500,000 to $17,000,000. For Fiscal 2001, the Company expects to achieve
revenue of approximately $74,000,000 and earnings per share of $0.05 excluding
charges.

The Company will host a conference call and simultaneous Webcast today, November
21, 2000, at 5:30PM Eastern time. Details will follow in this release.

The Company also announced Mark Housley has stepped down as President and Chief
Operating Officer of Media 100 for personal reasons. He will continue to serve
on the Company's board of directors.

John Molinari, Chief Executive Officer of Media 100 said, "Although fourth
quarter performance is disappointing, we continue to see strong prospects for
the Company as we ramp up shipments of Cleaner 5 streaming software and new
products come online in the quarters ahead."

The Company plans to announce its fiscal fourth quarter and full year results in
the first half of January 2001.

                                   -- MORE --



ABOUT MEDIA 100

Media 100 is the leading supplier of software, systems and services for
streaming media on the Internet. Media 100 develops software and systems that
simplify the creation and delivery of video on the Internet, DVD and CD-ROM.
Media 100 also provides the most comprehensive suite of streaming media services
to its customers by offering encoding (audio and video compression) and hosting
(delivery) services for Internet broadcasters, web designers and digital media
content creators. For more information, visit www.media100.com.


THIS PRESS RELEASE CONTAINS FORWARD-LOOKING STATEMENTS THAT ARE BASED ON CURRENT
EXPECTATIONS. ACTUAL RESULTS COULD DIFFER MATERIALLY FROM THOSE PROJECTED IN THE
FORWARD-LOOKING STATEMENTS AS A RESULT OF VARIOUS RISKS AND UNCERTAINTIES,
INCLUDING CONTINUED DEMAND FOR AND MARKET ACCEPTANCE OF THE COMPANY'S PRODUCTS,
TECHNICAL RISK IN DEVELOPING PRODUCTS CONTAINING NEW TECHNOLOGIES, THE COMPANY'S
ABILITY TO SUCCESSFULLY INTRODUCE AND ACHIEVE MARKET ACCEPTANCE FOR NEW
PRODUCTS, COMPETITIVE PRESSURES AND OTHER FACTORS DESCRIBED IN THE COMPANY'S
ANNUAL REPORT ON FORM 10-K FOR THE FISCAL YEAR ENDED NOVEMBER 30, 1999 FILED
WITH THE SECURITIES AND EXCHANGE COMMISSION.

                          CONFERENCE CALL INFORMATION:

Please Dial:

800.231.9012 (U.S. CALLERS)
719.457.2617  (INT'L. CALLERS)

Please ask for the Media 100 Inc. conference call, hosted by John Molinari and
Steve Shea.

A replay of the conference call will be available approximately one hour after
the conclusion of the call until Thursday, November 23 at 5:30PM

To access the replay, please dial:

888.203.1112
719.457.0820
Passcode:  603572
(the passcode will be necessary when accessing the replay)

                              WEBCAST INFORMATION:

Go to -- http://www.media100.com/corporate/investormain.html -- and click on the
StreetEvents link.

                                       ###