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Net Loss Per Share (Details) - $ / shares
9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Warrant, exercise price (in dollars per share) $ 75.90  
Warrant, exercise period (in years) 5 years  
Stock options    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive stock options outstanding (in shares) 1,364,000 989,000
Restricted Stock Unit Awards    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive stock options outstanding (in shares) 468,000 375,000
Convertible Debt Securities | Convertible Notes | Convertible Senior Notes due 2024    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive stock options outstanding (in shares) 638,051  
Initial conversion price (in dollars per share) $ 46.4037  
Convertible Debt Securities | Convertible Notes | Convertible Senior Notes Due 2026    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive stock options outstanding (in shares) 3,700,272  
Initial conversion price (in dollars per share) $ 30.8356  
Convertible Debt Securities | Convertible Notes | Convertible Senior Notes Due 2027    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Anti-dilutive stock options outstanding (in shares) 4,732,132  
Initial conversion price (in dollars per share) $ 17.8571