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Income Taxes - Schedule of effective income tax rate reconciliation (Details)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Computation of Effective Income Tax Rate [Abstract]    
Federal statutory tax rate 21.00% 34.00%
State taxes 4.40% (0.90%)
Non deductible expenses (0.60%) 19.40%
Tax credits 4.60% (90.60%)
Expired tax credits (3.90%) 0.00%
Stock based compensation 0.80% (69.60%)
Foreign income tax rate differential 0.00% (14.00%)
Repatriation Tax 0.00% 110.50%
Impact of Tax Cuts and Jobs Act enactment 0.00% 1241.00%
Valuation allowance (167.00%) 0.00%
Tax return and audit adjustments 0.00% (107.30%)
Contingent purchase revaluation (1.00%) (88.00%)
Other (0.10%) (1.70%)
Total (141.80%) 1032.80%