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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0000914121-10-001055.txt : 20100312
<SEC-HEADER>0000914121-10-001055.hdr.sgml : 20100312
<ACCEPTANCE-DATETIME>20100312190924
ACCESSION NUMBER:		0000914121-10-001055
CONFORMED SUBMISSION TYPE:	3/A
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20091231
FILED AS OF DATE:		20100312
DATE AS OF CHANGE:		20100312

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NUVEEN INSURED MASSACHUSETTS TAX FREE ADVANTAGE MUNICIPAL FUND
		CENTRAL INDEX KEY:			0001196366
		IRS NUMBER:				362639476
		STATE OF INCORPORATION:			MA

	BUSINESS ADDRESS:	
		STREET 1:		333 W WACKER DR
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60606
		BUSINESS PHONE:		3129178146

	MAIL ADDRESS:	
		STREET 1:		333 WEST WACKER DRIVE
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60606

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NUVEEN INSURED MASSACHUSET TAX FREE ADVANTAGE MUNICIPAL FUND
		DATE OF NAME CHANGE:	20021004

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BANK OF AMERICA CORP /DE/
		CENTRAL INDEX KEY:			0000070858
		STANDARD INDUSTRIAL CLASSIFICATION:	NATIONAL COMMERCIAL BANKS [6021]
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	811-21216
		FILM NUMBER:		10679251

	BUSINESS ADDRESS:	
		STREET 1:		BANK OF AMERICA CORPORATE CENTER
		STREET 2:		100 N TRYON ST
		CITY:			CHARLOTTE
		STATE:			NC
		ZIP:			28255
		BUSINESS PHONE:		7043868486

	MAIL ADDRESS:	
		STREET 1:		BANK OF AMERICA CORPORATE CENTER
		STREET 2:		100 N TRYON ST
		CITY:			CHARLOTTE
		STATE:			NC
		ZIP:			28255

	FORMER NAME:	
		FORMER CONFORMED NAME:	BANKAMERICA CORP/DE/
		DATE OF NAME CHANGE:	19981022

	FORMER NAME:	
		FORMER CONFORMED NAME:	NATIONSBANK CORP
		DATE OF NAME CHANGE:	19920703

	FORMER NAME:	
		FORMER CONFORMED NAME:	NCNB CORP
		DATE OF NAME CHANGE:	19920107

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BANK OF AMERICA NA
		CENTRAL INDEX KEY:			0001102113

	FILING VALUES:
		FORM TYPE:		3/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	811-21216
		FILM NUMBER:		10679250

	BUSINESS ADDRESS:	
		STREET 1:		100 N. TRYON STREET
		CITY:			CHARLOTTE
		STATE:			NC
		ZIP:			28255
		BUSINESS PHONE:		(704) 386-5494

	MAIL ADDRESS:	
		STREET 1:		100 N. TRYON STREET
		CITY:			CHARLOTTE
		STATE:			NC
		ZIP:			28255

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Blue Ridge Investments, L.L.C.
		CENTRAL INDEX KEY:			0001453700
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		3/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	811-21216
		FILM NUMBER:		10679249

	BUSINESS ADDRESS:	
		STREET 1:		214 NORTH TRYON STREET
		CITY:			CHARLOTTE
		STATE:			NC
		ZIP:			28255
		BUSINESS PHONE:		980-388-5633

	MAIL ADDRESS:	
		STREET 1:		214 NORTH TRYON STREET
		CITY:			CHARLOTTE
		STATE:			NC
		ZIP:			28255
</SEC-HEADER>
<DOCUMENT>
<TYPE>3/A
<SEQUENCE>1
<FILENAME>p18148477-3a_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0203</schemaVersion>

    <documentType>3/A</documentType>

    <periodOfReport>2009-12-31</periodOfReport>

    <dateOfOriginalSubmission>2010-01-15</dateOfOriginalSubmission>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001196366</issuerCik>
        <issuerName>NUVEEN INSURED MASSACHUSETTS TAX FREE ADVANTAGE MUNICIPAL FUND</issuerName>
        <issuerTradingSymbol>NGX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000070858</rptOwnerCik>
            <rptOwnerName>BANK OF AMERICA CORP /DE/</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>BANK OF AMERICA CORPORATE CENTER</rptOwnerStreet1>
            <rptOwnerStreet2>100 N TRYON STREET</rptOwnerStreet2>
            <rptOwnerCity>CHARLOTTE</rptOwnerCity>
            <rptOwnerState>NC</rptOwnerState>
            <rptOwnerZipCode>28255</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001102113</rptOwnerCik>
            <rptOwnerName>BANK OF AMERICA NA</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>100 N. TRYON STREET</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>CHARLOTTE</rptOwnerCity>
            <rptOwnerState>NC</rptOwnerState>
            <rptOwnerZipCode>28255</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001453700</rptOwnerCik>
            <rptOwnerName>Blue Ridge Investments, L.L.C.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>214 NORTH TRYON STREET</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>CHARLOTTE</rptOwnerCity>
            <rptOwnerState>NC</rptOwnerState>
            <rptOwnerZipCode>28255</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Auction Rate Preferred</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>45</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Subsidiary</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The Auction Rate Preferred Shares (&quot;Shares&quot;) reported in Table 1 represent 43 Shares beneficially owned by Blue Ridge
 Investments, L.L.C. (&quot;Blue Ridge&quot;) and 2 Shares beneficially owned by Bank of America, N.A. (&quot;BANA&quot;). Blue Ridge and BANA
 are each indirect, wholly owned subsidiaries of Bank of America Corporation (&quot;Bank of America&quot;).</footnote>
        <footnote id="F2">The Reporting Persons are filing this Form 3/A to indicate that the Form 3 previously filed on January 15, 2010 (the
 &quot;Original Form 3&quot;) was filed in error. The Original Form 3 was not required to be filed because the Reporting Persons were
 not as of the event date of the Original Form 3, and currently are not, beneficial owners of more than 10% of a class of
 equity securities of the Issuer.</footnote>
    </footnotes>

    <remarks>The Shares reported herein represent Bank of America's combined holdings in multiple series of auction rate preferred
 securities of the issuer, which are treated herein as one class of securities in accordance with the Auction Rate
 Securities--Global Exemptive Relief no-action letter issued by the Securities and Exchange Commission (&quot;SEC&quot;) on September
 22, 2008.</remarks>

    <ownerSignature>
        <signatureName>Bank of America Corporation and Bank of America, N.A. By: /s/ Debra I. Cho, Senior Vice President</signatureName>
        <signatureDate>2010-03-12</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Blue Ridge Investments, L.L.C. By: /s/ John Hiebendahl, Vice President and Controller</signatureName>
        <signatureDate>2010-03-12</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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