exhibit99.htm

July 28, 2009

First Midwest Bancorp, Inc.

Keefe, Bruyette & Woods

Investment Conference

Forward Looking Statements

This presentation may contain, and during this presentation our management may
make statements that may constitute “forward-looking statements” within the
meaning of the safe harbor provisions of the Private Securities Litigation Reform Act
of 1995. Forward-looking statements are not historical facts but instead represent
only our beliefs regarding future events, many of which, by their nature, are
inherently uncertain and outside our control. Forward-looking statements include,
among other things, statements regarding our financial performance, business
prospects, future growth and operating strategies, objectives and results. Actual
results, performance or developments could differ materially from those expressed
or implied by these forward-looking statements. Important factors that could cause
actual results to differ from those in the forward-looking statements include, among
others, those discussed in our Annual Report on Form 10-K and other reports filed
with the Securities and Exchange Commission, copies of which will be made
available upon request. With the exception of fiscal year end information previously
included in our Annual Report on Form 10-K, the information contained herein is
unaudited. Except as required by law, we undertake no duty to update the contents
of this presentation after the date of this presentation.

First Midwest Presentation Index

Who We Are

Credit Quality

Capital Position

Core Profitability

Why First Midwest

Who We Are

A Premier Bank	Premier Bank For Commercial	Premier Bank For Retail
$7.8 billion assets $5.8 billion deposits -66% core transactional -90% Suburban Chicago $5.3 billion loans $3.6 billion trust/investment aum	Seven business lines 25,000 commercial 1,600 trust relationships 200 relationship managers Tenured sales force and market presence	225,000 retail relationships 1,000 bankers 95 offices 8th largest distribution network in MSA 13th in Chicago MSA Market Share

Source: Commercial and retail relationships obtained from Harte Hanks Marketing Customer Information System as of 3/31/09

A Premier Community Bank

90% Suburban Chicago

Credit Quality

(1) As of 2Q09

Total Consumer - 13%

Home Equity Dominated

No Subprime Loans

No Credit Card

Conservative Underwriting

Construction And Development (1)

Performing Commercial Construction Portfolio

Residential NPL % Impacted By Continuing Illiquid
Residential Real Estate Market

Substantial Reserves

Current Valuations

As of 2Q09

	3Q08	4Q08	1Q09	2Q09
Loan Loss Reserve / Loans	1.34%	1.75%	2.15%	2.40%
LLR / (Non Accrual + 90 Day)	77%	57%	45%	52%
Non Accrual + 90 Day / Total Loans	1.74%	3.07%	4.78%	4.60%

(Non Accrual + 90 Day) / Total Loans

Loan Loss Reserve & Net Charge-offs

(1) Includes accruing and non-accruing Troubled Debt Restructures (TDRs)

(1)

Improved Delinquencies

Better Positioned To Reduce Problem Debts

Credit Focus

Early Identification And Remediation

Expanded Resources

Problem Resolution Strategies

Restructure

Accelerate Control

Varied Liquidation Strategies

Capital Position

Substantially Exceed “Well Capitalized” (1)

Built Capital Ratios Through Operating Performance, De
-leveraging Securities, And Issue Of Preferred Stock

(1) “Well Capitalized” minimum ratios (- - -) are currently 6% for Tier 1, 10% for Total Capital, and 4% for Tier 1 Common (applied to Supervisory Capital Assessment Program
tests on top 19 US banks)

“Well Capitalized” minimum ratios are currently 6% for Tier 1, 10% for Total Capital, and 4% for Tier 1 Common (applied to Supervisory Capital Assessment Program tests on top 19 US
banks)

Excess over “Well Capitalized” grossed up using 39% marginal tax rate

Represents the Pre-tax equivalent, excluding the $193 million in regulatory capital received by FMBI through the sale of preferred shares to the US Treasury as part of its Capital Purchase
Plan

Excess Regulatory Capital

Core Profitability

Operating Leverage - Most Recent Quarter ’09 (4)
Well Above Peers

	First Midwest	Metro Peers(1)	Chicago Peers(2)
PTPP Return on Average Assets(3)	1.98%	1.46%	1.03%

Core Drivers:
Net Interest Margin	3.64%	3.36%	2.65%
Efficiency	51%	65%	68%

Data represents the peer median core performance as reported by SNL Financial

The Metro Peers consist of AMFI, BOKF, CBSH, CFR, FCF, FULT, MBFI, ONB, SUSQ, UCBH, VLY, WTNY, and WTFC

The Chicago Peers consist of AMFI, MBFI, MBHI, OSBC, TAYC, and WTFC

Pre-tax, Pre-provision Operating Income (PTPP) excludes taxes, provision for loan losses, and market related security gains (losses) from reported quarter; PTPP is
computed on a fully tax equivalent basis

As of 1Q09

Almost Double

Greater Ability To Organically Generate Capital

Net Interest Margin

Efficiency

Excludes special FDIC assessment and market value adjustment on deferred compensation for 2Q09

The Metro Peers consist of AMFI, BOKF, CBSH, CFR, FCF, FULT, MBFI, ONB, SUSQ, UCBH, VLY, WTNY, and WTFC

The Chicago Peers consist of AMFI, MBFI, MBHI, OSBC, TAYC, and WTFC

Consistently Outperform Peers (2) (3)

Pre-Tax, Pre-Provision Earnings excludes taxes, provision for loan losses, and market related security gains (losses) from the reported quarter and the special FDIC assessment
levied in second quarter 2009

The Efficiency Ratio for second quarter 2009 has been adjusted to exclude the impact of the special FDIC assessment

2nd Quarter Performance

“Well Capitalized” minimum ratios are currently 6% for Tier 1, 10% for Total Capital, and 4% for Tier 1 Common (applied to Supervisory Capital Assessment Program tests on top 19 US
banks)

Excess over “Well Capitalized” grossed up using 39% marginal tax rate

Represents the pre-tax equivalent, excluding the $193 million in regulatory capital received by FMBI through the sale of preferred shares to the US Treasury as part of its Capital Purchase
Plan

Annualized 2Q09 Pre-Tax, Pre-Provision Operating Income (PTPP) excludes taxes, provision for loan losses, and market related security gains (losses)

Excess Regulatory Capital + Operating
Leverage

Why First Midwest

Strong Franchise

Navigating Reality Of Cycle

Proactive Remediation Of Credit

Solid Capital

Leveraging Operating Performance

Strengthening Core Business

Relationship-Based Lending

Core Deposit Expansion

Able To Benefit From Market Disruption

Well Positioned For Recovery