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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 V+k8DBQCpaVUFMKvKiTL3dj6Dkbx9ZjmMb5A3QzVcr6Cg5YfX2v0QHcavZw3pnBM
 iOP21C3Phpv7zZcLG1yZsg==

<SEC-DOCUMENT>0000702325-08-000115.txt : 20080819
<SEC-HEADER>0000702325-08-000115.hdr.sgml : 20080819
<ACCEPTANCE-DATETIME>20080819162729
ACCESSION NUMBER:		0000702325-08-000115
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080816
FILED AS OF DATE:		20080819
DATE AS OF CHANGE:		20080819

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			FIRST MIDWEST BANCORP INC
		CENTRAL INDEX KEY:			0000702325
		STANDARD INDUSTRIAL CLASSIFICATION:	NATIONAL COMMERCIAL BANKS [6021]
		IRS NUMBER:				363161078
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		ONE PIERCE PLACE
		STREET 2:		SUITE 1500
		CITY:			ITASCA
		STATE:			IL
		ZIP:			60143
		BUSINESS PHONE:		6308757450

	MAIL ADDRESS:	
		STREET 1:		ONE PIERCE PLACE
		STREET 2:		SUITE 1500
		CITY:			ITASCA
		STATE:			IL
		ZIP:			60143

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Hotchkiss James P
		CENTRAL INDEX KEY:			0001435561

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-10967
		FILM NUMBER:		081027920

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		630 875 7450

	MAIL ADDRESS:	
		STREET 1:		ONE PIERCE PLACE
		STREET 2:		SUITE 1500
		CITY:			ITASCA
		STATE:			IL
		ZIP:			60143
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>hot726.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-08-16</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000702325</issuerCik>
        <issuerName>FIRST MIDWEST BANCORP INC</issuerName>
        <issuerTradingSymbol>FMBI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001435561</rptOwnerCik>
            <rptOwnerName>Hotchkiss James P</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE PIERCE PLACE, SUITE 1500</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ITASCA</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60143</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>EVP, Treasurer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2008-08-16</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>F</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>178</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>23.7850</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3409</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1762</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Profit Sharing Plan Trust</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">On August 16, 2006 the Issuer granted the Reporting Person a Restricted Stock Award (RSA) of 1,208 restricted shares of First Midwest Bancorp, Inc. Common Stock under the First Midwest Bancorp, Inc. Omnibus Stock Incentive Plan (Plan) which were scheduled to vest in two equal annual installments on the first and second anniversary of the date of grant.  On August 16, 2008, 604 shares of the originally granted RSAs vested, of which 178 shares were surrendered by the Reporting Person in order to satisfy tax withholding obligations.  This form is being filed to reflect the surrender of such shares to satisfy the Reporting Person?s tax withholding obligation.</footnote>
        <footnote id="F2">Between July 30, 2008 and August 19, 2008 the Reporting Person acquired 3 shares of First Midwest Bancorp, Inc. Common Stock under the First Midwest Bancorp, Inc. Savings and Profit Sharing Plan pursuant to payroll contributions.  This information is based on a plan statement dated August 7, 2008.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>By: Andrea L. Stangl, Attorney-in-fact for James P. Hotchkiss</signatureName>
        <signatureDate>2008-08-19</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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