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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 HdRo6bQSBr/GRUCjV8oaACL7mokR6KRrwA6DD/tiZiLr0fL6Z3KQX0BDDk7ETcG/
 KE0pSGFT8liNhTrknQCdfw==

<SEC-DOCUMENT>0000702325-08-000073.txt : 20080523
<SEC-HEADER>0000702325-08-000073.hdr.sgml : 20080523
<ACCEPTANCE-DATETIME>20080523170945
ACCESSION NUMBER:		0000702325-08-000073
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080521
FILED AS OF DATE:		20080523
DATE AS OF CHANGE:		20080523

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			FIRST MIDWEST BANCORP INC
		CENTRAL INDEX KEY:			0000702325
		STANDARD INDUSTRIAL CLASSIFICATION:	NATIONAL COMMERCIAL BANKS [6021]
		IRS NUMBER:				363161078
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		ONE PIERCE PLACE
		STREET 2:		SUITE 1500
		CITY:			ITASCA
		STATE:			IL
		ZIP:			60143
		BUSINESS PHONE:		6308757450

	MAIL ADDRESS:	
		STREET 1:		ONE PIERCE PLACE
		STREET 2:		SUITE 1500
		CITY:			ITASCA
		STATE:			IL
		ZIP:			60143

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Lance Cynthia A
		CENTRAL INDEX KEY:			0001399159

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-10967
		FILM NUMBER:		08858873

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		630 875 7450

	MAIL ADDRESS:	
		STREET 1:		ONE PIERCE PLACE, SUITE 1500
		CITY:			ITASCA
		STATE:			IL
		ZIP:			60143
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>lan693.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-05-21</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000702325</issuerCik>
        <issuerName>FIRST MIDWEST BANCORP INC</issuerName>
        <issuerTradingSymbol>FMBI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001399159</rptOwnerCik>
            <rptOwnerName>Lance Cynthia A</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE PIERCE PLACE, SUITE 1500</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ITASCA</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60143</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>EVP, Corporate Secretary</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
                <footnoteId id="F1"/>
                <footnoteId id="F2"/>
            </securityTitle>
            <transactionDate>
                <value>2008-05-21</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>603</value>
                    <footnoteId id="F3"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2075</value>
                    <footnoteId id="F4"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>262</value>
                    <footnoteId id="F5"/>
                    <footnoteId id="F6"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Profit Sharing Plan Trust</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Restricted Stock Awards (RSAs) granted pursuant to the Restated First Midwest Bancorp, Inc. Omnibus Stock and Incentive Plan.</footnote>
        <footnote id="F2">The RSAs will vest in two equal installments, specifically on the first and second anniversaries of the date of grant, however, each RSA will vest in full upon the Reporting Person's retirement from the Issuer.</footnote>
        <footnote id="F3">The number of RSAs awarded to the reporting person was determined by dividing the sum of the total dollar value granted to the reporting person by $24.79 (average of the highest and lowest prices of the Issuer's Common Stock as reported by Nasdaq on May 21, 2008).</footnote>
        <footnote id="F4">Between May 18, 2007 and May 23, 2008 the reporting person acquired 58 shares of First Midwest common stock under the First Midwest Bancorp, Inc. Dividend Reinvestment Plan.  The information in this report is based on a plan statement dated April 15, 2008.</footnote>
        <footnote id="F5">Between May 18, 2007 and May 23, 2008 the reporting person acquired 18 shares of First Midwest common stock pursuant to the dividend reinvestment feature under the First Midwest Bancorp, Inc. Savings and Profit Sharing Plan.  The information in this report is based on a plan statement dated April 22, 2008.</footnote>
        <footnote id="F6">Between May 18, 2008 and May 23, 2008 the reporting person acquired 244 shares of First Midwest Bancorp, Inc. common stock under the First Midwest Bancorp, Inc. Savings and Profit Sharing Plan.  The information in this report is based on a plan statement dated May 14, 2008.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>By: Andrea L. Stangl, Attorney-in-fact</signatureName>
        <signatureDate>2008-05-23</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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