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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0000702325-08-000059.txt : 20080520
<SEC-HEADER>0000702325-08-000059.hdr.sgml : 20080520
<ACCEPTANCE-DATETIME>20080520195237
ACCESSION NUMBER:		0000702325-08-000059
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080516
FILED AS OF DATE:		20080520
DATE AS OF CHANGE:		20080520

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			FIRST MIDWEST BANCORP INC
		CENTRAL INDEX KEY:			0000702325
		STANDARD INDUSTRIAL CLASSIFICATION:	NATIONAL COMMERCIAL BANKS [6021]
		IRS NUMBER:				363161078
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		ONE PIERCE PLACE
		STREET 2:		SUITE 1500
		CITY:			ITASCA
		STATE:			IL
		ZIP:			60143
		BUSINESS PHONE:		6308757450

	MAIL ADDRESS:	
		STREET 1:		ONE PIERCE PLACE
		STREET 2:		SUITE 1500
		CITY:			ITASCA
		STATE:			IL
		ZIP:			60143

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SCUDDER MICHAEL L
		CENTRAL INDEX KEY:			0001199246

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-10967
		FILM NUMBER:		08850291

	MAIL ADDRESS:	
		STREET 1:		300 PARK BLVD
		STREET 2:		SUITE 405
		CITY:			ITASCA
		STATE:			IL
		ZIP:			60143
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>scu674.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-05-16</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000702325</issuerCik>
        <issuerName>FIRST MIDWEST BANCORP INC</issuerName>
        <issuerTradingSymbol>FMBI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001199246</rptOwnerCik>
            <rptOwnerName>SCUDDER MICHAEL L</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE PIERCE PLACE, SUITE 1500</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ITASCA</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60143</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President &amp; COO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2008-05-16</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>F</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>654</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>25.1100</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>12052</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>8444</value>
                    <footnoteId id="F3"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By NQ Stock Option Gain Deferral Plan</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>5349</value>
                    <footnoteId id="F4"/>
                    <footnoteId id="F5"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Profit Sharing Plan Trust</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">On May 16, 2007 the Issuer granted the reporting person 4,435 Restricted Stock Awards (RSAs) under the First Midwest Bancorp, Inc. Omnibus Stock Incentive Plan (Plan). On May 16, 2008, 2,218 shares of the originally granted RSAs vested, of which 654 shares were surrendered by the reporting person in order to satisfy tax withholding obligations.  This form is being filed to reflect the surrender of such shares to satisfy the reporting person?s tax withholding obligation.</footnote>
        <footnote id="F2">Between March 6, 2008 and May 20, 2008 the reporting person acquired 12 shares of First Midwest common stock under the First Midwest Bancorp, Inc. Dividend Reinvestment Plan.  The information  in this report is based on a plan statement dated April 15, 2008.</footnote>
        <footnote id="F3">Between March 6, 2008 and May 20, 2008 the reporting person acquired 99 shares of First Midwest common stock pursuant to the dividend reinvestment feature under the First Midwest Bancorp, Inc. Non-Qualified Gain Deferral Plan.  The information in this report is based on a plan statement dated April 15, 2008.</footnote>
        <footnote id="F4">Between March 6, 2008 and May 20, 2008 the reporting person acquired 60 shares of First Midwest common stock pursuant to the dividend reinvestment feature under the First Midwest Bancorp, Inc. Savings and Profit Sharing Plan. The information in this report is based on a plan statement dated April 22, 2008.</footnote>
        <footnote id="F5">Between March 6, 2008 and May 20, 2008 the reporting person acquired 46 shares of First Midwest Bancorp, Inc. common stock under the First Midwest Bancorp, Inc. Savings and Profit Sharing Plan.  The information in this report is based on a plan statement dated May 14, 2008.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>By: Andrea L. Stangl, Attorney-in-fact</signatureName>
        <signatureDate>2008-05-20</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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