Document

Exhibit 21

SUBSIDIARIES OF APPLIED MATERIALS, INC.

As of October 30, 2022

LEGAL ENTITY NAME

PLACE OF
INCORPORATION

Applied Materials (Holdings)

(1)

California

Applied Materials Asia-Pacific, LLC

(2) (3)

Delaware

Applied Materials Canada, Inc.

Canada

Applied Materials Holdings S.à r.l.

(4)

Luxembourg

Applied Materials India Private Limited

India

Applied Materials Israel Ltd.

(5)

Israel

Applied Materials Netherlands B.V.

(3) (6)

The Netherlands

Applied Ventures, LLC

(7) (8) (9)

Delaware

Semitool, Inc.

Montana

Tango Systems LLC

(10)

Delaware

Varian Semiconductor Equipment Associates, Inc.

(11)

Delaware

Veranome Biosystems LLC

Delaware

(1) Applied Materials (Holdings) owns the following subsidiary:

Applied Materials UK Limited

California

(2) Applied Materials Asia-Pacific, LLC owns the following subsidiaries:

Applied Materials (China) Holdings, Ltd.

(a)

P.R. China

Applied Materials China, Limited

(b)

Hong Kong

(3) Applied Materials Asia-Pacific, LLC and Applied Materials Netherlands B.V. each partially owns the following subsidiary:

Applied Materials Taiwan, Ltd.

Taiwan

(4) Applied Materials Holdings S.à r.l. owns the following subsidiaries:

Applied Materials Luxembourg 2 S.à r.l.

Luxembourg

Applied Materials U.S. Holdings LLC

Delaware

(5) Applied Materials Israel Ltd. owns the following subsidiary:

ICT Integrated Circuit Testing GmbH

Germany

LEGAL ENTITY NAME

PLACE OF INCORPORATION

(6) Applied Materials Netherlands B.V. owns the following subsidiaries:

Applied Materials Belgium N.V.

Belgium

Applied Materials Deutschland Holding GmbH

(c)

Germany

Applied Materials France

France

Applied Materials GmbH

(d)

Germany

Applied Materials Ireland Limited

Ireland

Applied Materials Italia S.r.l.

Italy

Applied Materials Japan, Inc.

(e)

Japan

Applied Materials Korea Ltd.

Korea

Picosun Oy

(f)

Finland

Think Silicon Single Member P.C.

Greece

(7) Applied Ventures, LLC owns the following subsidiaries:

Applied Ventures Investment Management GP I, LLC

(g)

Delaware

Applied Ventures Investment Management GP II, LLC

(h)

Delaware

(8) Applied Ventures, LLC owns 50% of the following subsidiary:

Applied Ventures ITIC Innovation Fund GP, LLC

(i)

Delaware

(9) Applied Ventures, LLC and Applied Materials South East Asia Pte. Ltd. own the following subsidiary:

Applied Ventures Innovation Fund II, L.P.

Delaware

(10) Tango Systems LLC owns the following subsidiary:

Kunshan Tango Semiconductor Equipment Co., Ltd.

P.R. China

(11) Varian Semiconductor Equipment Associates, Inc. owns the following subsidiaries:

Applied Materials Global Venture Partner Pte. Ltd.

Singapore

Applied Materials South East Asia Pte. Ltd.

(g) (j)

Singapore

(a) Applied Materials (China) Holdings, Ltd. owns the following subsidiary:

Applied Materials (Xi'an), Ltd.

P.R. China

(b) Applied Materials China, Limited owns the following subsidiaries:

Applied Materials (China), Inc.

P.R. China

Applied Materials Display Equipment (Shanghai) Co., Ltd.

P.R. China

Lin-gang Special Area Applied Materials (Shanghai) Co., Ltd.

P.R. China

Applied Materials GmbH & Co. KG

(k)

Germany

Applied Materials Verwaltung GmbH

Germany

Mecatronix GmbH

Germany

LEGAL ENTITY NAME

PLACE OF INCORPORATION

(d) Applied Materials GmbH owns the following subsidiary:

Picosun Europe GmbH

Germany

(e) Applied Materials Japan, Inc. owns the following subsidiaries:

Picosun Japan Co., Ltd.

Japan

Sigmameltec Ltd.

Japan

(f) Picosun Oy owns the following subsidiaries:

Picosun (Suzhou) Nanotechnology Co., Ltd.

P.R. China

Picosun Asia Pte. Ltd.

Singapore

Picosun Korea Limited

Korea

Picosun USA LLC

Michigan

Picosun Taiwan Co. Ltd.

Taiwan

(g) Applied Ventures Investment Management GP I, LLC and Applied Materials South East Asia Pte. Ltd., collectively own 60% of the following subsidiary:

Applied Ventures Innovation Fund I, L.P.

Delaware

(h) Applied Ventures Investment Management GP II, LLC owns the following subsidiary:

Applied Ventures Innovation Fund II, L.P.

Delaware

(i) Applied Ventures ITIC Innovation Fund GP, LLC and Applied Materials, Inc. collectively own 31% of the following subsidiary:

Applied Ventures ITIC Innovation Fund, L.P.

Delaware

(j) Applied Materials South East Asia Pte. Ltd. owns the following subsidiaries:

Applied Materials Europe B.V.

The Netherlands

Applied Materials Hong Kong Limited

(l)

Hong Kong

Applied Materials Korea Innovation and Technology, LLC

Korea

Applied Materials Philippines LLC

Nevada

Applied Materials Singapore Technology Pte. Ltd.

Singapore

MDLSoft LLC

(m)

Delaware

Perceptive Engineering Limited

(n)

United Kingdom

Sage Design Automation, Ltd.

(o)

Israel

(k) Applied Materials GmbH & Co. KG owns the following subsidiary:

Applied Materials WEB Coating GmbH

Germany

(l) Applied Materials Hong Kong Limited owns the following subsidiary:

Baccini Pte. Ltd.

Singapore

(m) MDLSoft LLC owns the following subsidiary:

MDLab S.r.l. in liquidation

Italy

(n) Perceptive Engineering Limited owns the following subsidiaries:

Perceptive Engineering Limited

Ireland

Perceptive Engineering Pte. Ltd.

Singapore

(o) Sage Design Automation, Ltd. owns the following subsidiaries:

Sage Design Automation LLC

California

NP Komplete Technologies, B.V.

The Netherlands