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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 BVRm9sw3a391hMhSgcvIJPuewSsHoE/4lsEP+9+UUwm7KExKTeRMSxJGOKgxnmKV
 mwVYRGmPoHwYOT2wgal29w==

<SEC-DOCUMENT>0001181431-06-004191.txt : 20060119
<SEC-HEADER>0001181431-06-004191.hdr.sgml : 20060119
<ACCEPTANCE-DATETIME>20060119120012
ACCESSION NUMBER:		0001181431-06-004191
CONFORMED SUBMISSION TYPE:	5
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20051231
FILED AS OF DATE:		20060119
DATE AS OF CHANGE:		20060119

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			KERSHAW PETER C
		CENTRAL INDEX KEY:			0001190846

	FILING VALUES:
		FORM TYPE:		5
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-09781
		FILM NUMBER:		06537277

	BUSINESS ADDRESS:	
		STREET 1:		HOLOGIC INC
		STREET 2:		35 CROSBY DR
		CITY:			BEDFORD
		STATE:			MA
		ZIP:			01730
		BUSINESS PHONE:		3026312877

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MILLIPORE CORP /MA
		CENTRAL INDEX KEY:			0000066479
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				042170233
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		290 CONCORD ROAD
		CITY:			BILLERICA
		STATE:			MA
		ZIP:			01821
		BUSINESS PHONE:		978-715-4321

	MAIL ADDRESS:	
		STREET 1:		290 CONCORD ROAD
		CITY:			BILLERICA
		STATE:			MA
		ZIP:			01821

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MILLIPORE CORP
		DATE OF NAME CHANGE:	19920703

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MILLIPORE FILTER CORP
		DATE OF NAME CHANGE:	19661116
</SEC-HEADER>
<DOCUMENT>
<TYPE>5
<SEQUENCE>1
<FILENAME>rrd104124.xml
<DESCRIPTION>ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERWSHIP
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>5</documentType>

    <periodOfReport>2005-12-31</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <form3HoldingsReported>0</form3HoldingsReported>

    <form4TransactionsReported>0</form4TransactionsReported>

    <issuer>
        <issuerCik>0000066479</issuerCik>
        <issuerName>MILLIPORE CORP /MA</issuerName>
        <issuerTradingSymbol>MIL</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001190846</rptOwnerCik>
            <rptOwnerName>KERSHAW PETER C</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>290 CONCORD ROAD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>BILLERICA</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>01820</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Vice President</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, $1.00 Par value</value>
            </securityTitle>
            <transactionCoding></transactionCoding>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>168.24</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Shares acquired under the Corporation's Employees' Stock Purchase Plan, a Section 423 plan, prior to termination of the Plan in February 2005.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>patricia a. powers, attorney in fact</signatureName>
        <signatureDate>2006-01-19</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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