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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 xm2qbA4KbhNTIaCa1fLmqw==

<SEC-DOCUMENT>0001181431-05-023872.txt : 20050427
<SEC-HEADER>0001181431-05-023872.hdr.sgml : 20050427
<ACCEPTANCE-DATETIME>20050427165217
ACCESSION NUMBER:		0001181431-05-023872
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050427
FILED AS OF DATE:		20050427
DATE AS OF CHANGE:		20050427

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MILLIPORE CORP /MA
		CENTRAL INDEX KEY:			0000066479
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				042170233
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		80 ASHBY RD
		CITY:			BEDFORD
		STATE:			MA
		ZIP:			01730
		BUSINESS PHONE:		7815336000

	MAIL ADDRESS:	
		STREET 1:		80 ASHBY ROAD
		CITY:			BEDFORD
		STATE:			MA
		ZIP:			01730

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MILLIPORE CORP
		DATE OF NAME CHANGE:	19920703

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MILLIPORE FILTER CORP
		DATE OF NAME CHANGE:	19661116

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			HOFFMAN MARK
		CENTRAL INDEX KEY:			0001228405

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-09781
		FILM NUMBER:		05776957

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		9787154321

	MAIL ADDRESS:	
		STREET 1:		C/O MILLIPORE CORP
		STREET 2:		80 ASHBY RD
		CITY:			BEDFORD
		STATE:			MA
		ZIP:			01820
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd76700.xml
<DESCRIPTION>STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-04-27</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000066479</issuerCik>
        <issuerName>MILLIPORE CORP /MA</issuerName>
        <issuerTradingSymbol>MIL</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001228405</rptOwnerCik>
            <rptOwnerName>HOFFMAN MARK</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>290 CONCORD ROAD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>BILLERICA</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>01821</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, $1.00 Par Value</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>15004.254</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Options (rights to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>47.10</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-04-27</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>2500</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2006-04-27</value>
            </exerciseDate>
            <expirationDate>
                <value>2015-04-27</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>common stock 1.00 par value</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>2500</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2500</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F1"/>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Stock options granted under the 1999 Stock Option Plan for Non-Employee Directors as provided under the terms of that Plan.  The reporting person also acquired, prior to June 2002, 2887.8 deferred compensation phantom stock units payable in cash upon retirement or termination of service.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>patricia a. powers, attorney in fact</signatureName>
        <signatureDate>2005-04-27</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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