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                                                                    Exhibit 23.1

                       CONSENT OF INDEPENDENT ACCOUNTANTS

We hereby consent to the use in this Registration Statement on Form S-4 of
Rosetta Inpharmatics, Inc. of our report dated January 26, 2001 relating to the
consolidated financial statements of Rosetta Inpharmatics, Inc., which appears
in such Registration Statement. We also consent to the references to us under
the heading Independent Public Accountants in such Registration Statement.

/s/ PricewaterhouseCoopers LLP

PricewaterhouseCoopers LLP

Seattle, Washington
May 25, 2001