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Consolidated Condensed Statements of Operations (Unaudited) - USD ($)
shares in Millions, $ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Income Statement [Abstract]        
Revenue (Note 2) $ 6,941.6 $ 6,772.8 $ 21,239.6 $ 20,318.5
Costs, expenses, and other:        
Cost of sales 1,579.1 1,430.8 5,081.7 5,262.6
Research and development 1,802.9 1,705.3 5,194.9 5,032.4
Marketing, selling, and administrative 1,614.2 1,577.9 4,797.2 4,839.6
Acquired in-process research and development and development milestones (Note 3) 62.4 177.6 668.4 532.4
Asset impairment, restructuring, and other special charges (Note 5) 206.5 0.0 206.5 211.6
Other–net, (income) expense (Note 11) 111.0 635.9 580.9 124.3
Costs, expenses, and other 5,376.1 5,527.5 16,529.6 16,002.9
Income before income taxes 1,565.5 1,245.3 4,710.0 4,315.6
Income taxes (Note 7) 113.8 135.2 402.9 460.0
Net income $ 1,451.7 $ 1,110.1 $ 4,307.1 $ 3,855.6
Earnings per share:        
Basic (in dollars per share) $ 1.61 $ 1.22 $ 4.78 $ 4.25
Diluted (in dollars per share) $ 1.61 $ 1.22 $ 4.76 $ 4.23
Shares used in calculation of earnings per share:        
Basic (in shares) 900.7 906.7 901.8 907.7
Diluted (in shares) 903.8 910.8 904.5 911.7