Revenue (Summary of Revenue Recognized) (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Disaggregation of Revenue [Line Items]
Revenue	$ 6,488.0	$ 6,740.1	$ 14,298.0	$ 13,545.7
Net product revenue
Disaggregation of Revenue [Line Items]
Revenue	5,870.9	6,070.5	13,003.8	12,390.5
Collaboration and other revenue
Disaggregation of Revenue [Line Items]
Revenue	617.1	669.6	1,294.2	1,155.2
Collaboration and other revenue associated with prior period transfers of intellectual property
Disaggregation of Revenue [Line Items]
Revenue	$ 34.4	$ 31.0	$ 87.6	$ 73.9