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Consolidated Condensed Statements of Operations (Unaudited) - USD ($)
shares in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Income Statement [Abstract]        
Revenue (Note 2) $ 6,488,000,000 $ 6,740,100,000 $ 14,298,000,000 $ 13,545,700,000
Costs, expenses, and other:        
Cost of sales 1,430,500,000 1,953,200,000 3,502,600,000 3,831,800,000
Research and development 1,781,900,000 1,655,000,000 3,392,000,000 3,327,100,000
Marketing, selling, and administrative 1,625,100,000 1,685,700,000 3,183,000,000 3,261,700,000
Acquired in-process research and development and development milestones (Note 3) 440,400,000 42,800,000 606,000,000.0 354,800,000
Asset impairment, restructuring, and other special charges (Note 5) 0 0 0 211,600,000
Other–net, (income) expense (Note 11) 119,200,000 (190,500,000) 469,900,000 (511,600,000)
Costs, expenses, and other 5,397,100,000 5,146,200,000 11,153,500,000 10,475,400,000
Income before income taxes 1,090,900,000 1,593,900,000 3,144,500,000 3,070,300,000
Income taxes (Note 7) 138,400,000 203,700,000 289,100,000 324,800,000
Net income $ 952,500,000 $ 1,390,200,000 $ 2,855,400,000 $ 2,745,500,000
Earnings per share:        
Basic (in dollars per share) $ 1.06 $ 1.53 $ 3.17 $ 3.02
Diluted (in dollars per share) $ 1.05 $ 1.53 $ 3.16 $ 3.01
Shares used in calculation of earnings per share:        
Basic (in shares) 900.3 907.3 902.0 908.2
Diluted (in shares) 902.9 910.4 904.4 911.6