Consolidated Condensed Statements of Cash Flows - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Cash Flows from Operating Activities
Net income	$ 1,902.9	$ 1,355.3
Adjustments to Reconcile Net Income to Cash Flows from Operating Activities:
Depreciation and amortization	435.7	350.3
Change in deferred income taxes	(506.6)	(119.1)
Stock-based compensation expense	101.0	85.5
Net investment (gains) losses	426.1	(302.2)
Acquired in-process research and development	153.0	299.3
Other changes in operating assets and liabilities, net of acquisitions and divestitures	(45.5)	(102.8)
Other non-cash operating activities, net	32.6	131.1
Net Cash Provided by Operating Activities	2,499.2	1,697.4
Cash Flows from Investing Activities
Net purchases of property and equipment	(365.4)	(300.3)
Proceeds from sales and maturities of short-term investments	26.7	4.0
Purchases of short-term investments	(14.6)	(19.4)
Proceeds from sales of noncurrent investments	81.4	284.8
Purchases of noncurrent investments	(116.7)	(291.5)
Cash paid for acquisitions, net of cash acquired (Note 3)	0.0	(747.4)
Purchases of in-process research and development	(491.8)	(191.8)
Other investing activities, net	(133.4)	(21.9)
Net Cash Used for Investing Activities	(1,013.8)	(1,283.5)
Cash Flows from Financing Activities
Dividends paid	(885.5)	(774.8)
Net change in short-term borrowings	499.7
Net change in short-term borrowings		(3.7)
Repayments of long-term debt	(710.1)	0.0
Purchases of common stock	(1,500.0)	0.0
Other financing activities, net	(282.4)	(279.9)
Net Cash Used for Financing Activities	(2,878.3)	(1,058.4)
Effect of exchange rate changes on cash and cash equivalents	33.6	(10.2)
Net decrease in cash and cash equivalents	(1,359.3)	(654.7)
Cash and cash equivalents at January 1	3,818.5	3,657.1
Cash and Cash Equivalents at March 31	$ 2,459.2	$ 3,002.4