Revenue (Summary of Revenue Recognized) (Details) - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Disaggregation of Revenue [Line Items]
Revenue	$ 7,810.0	$ 6,805.6
Net product revenue
Disaggregation of Revenue [Line Items]
Revenue	7,132.9	6,320.0
Collaboration and other revenue
Disaggregation of Revenue [Line Items]
Revenue	677.1	485.6
Collaboration and other revenue associated with prior period transfers of intellectual property
Disaggregation of Revenue [Line Items]
Revenue	$ 53.2	$ 43.0