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Revenue (Summary of Revenue Recognized) (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Disaggregation of Revenue [Line Items]        
Revenue $ 5,499.4 $ 5,636.7 $ 11,359.2 $ 10,728.9
Net product revenue        
Disaggregation of Revenue [Line Items]        
Revenue 5,077.7 5,168.7 10,481.2 9,861.0
Collaboration and other revenue        
Disaggregation of Revenue [Line Items]        
Revenue 421.7 468.0 878.0 867.9
Collaboration and other revenue associated with prior period transfers of intellectual property        
Disaggregation of Revenue [Line Items]        
Revenue $ 34.7 $ 59.6 $ 70.0 $ 95.1